“…d) In short, flow-through ISFETs arrangements have been applied in on-line blood electrolyte monitoring (1081, in biotechnology [ 1241, in the measurement of environmental parameters [117, 1231, but especially in clinical analysis for determining parameters in serum [114, 1291, in blood [l lo], and for in vivo blood monitoring [112]. On the other hand, flowthrough ISE approaches have been used more in environmental monitoring, especially for water samples: freshwater [67], natural water [43,76,791, tap water [27,47,50,84,88, 931, seawater [63], wastewater [52, 74, 761, and effluents [77, 781, but also for soils [39,44,981 and rock salts (431. Also the clinical applications of ISEs working in flowing systems are numerous: serum [31,33,34,35,421, plasma [37], blood [68], and urine [84] have been the commonest target samples.…”