INTRODUCTIONOne of the emerging trends in higher education in Asian countries is English-medium instruction (EMI), which uses English as the primary instructional language [1]. EMI has been widely used across diverse disciplines, including nursing, with the expectation of preparing domestic students for leadership and of attracting promising foreign students in the era of internationalization [2]. In addition to the number of foreign professors and students, the number of English-medium courses (EMCs) is one of the criteria by which Korean colleges are evaluated [3,4]. As of 2013, EMCs comprised 30~40% of the courses offered at prestigious universities in Korea [5].As EMI increases in popularity, the feasibility and effectiveness of this instructional method have received attention from educators and researchers. Although faculty and students agree on the need for EMI and students have benefitted from the instructional method, significant numbers of them have experienced difficulty College of Nursing, Seoul National University, Seoul, KoreaPurpose: An emerging trend in Asian higher education is English-medium instruction (EMI), which uses English as the primary instructional language. EMI prepares domestic students for international leadership; however, students report difficulty in learning, and educators have raised questions concerning the effectiveness of EMI. The flipped learning model (FLM), in which lecture and homework activities for a course are reversed, was applied to an English-medium course offered by a college of nursing in Korea.The aims of this study were to: 1) revise an existing English-medium nursing course using the FLM; 2) explore students' learning experiences and their acceptance of the FLM; and 3) identify key factors in the success of FLM. Methods: We used a descriptive, cross-sectional, mixed-methods design and the participants were students at one nursing school in Korea. A series of course development meetings with faculties from the nursing school and the center for teaching and learning were used to develop the course format and content. We conducted course evaluations using the Flipped Course Evaluation Questionnaire with open-ended questions and focus group interviews. Results: Students (N=75) in a 15-week nursing course responded to a survey after completing the course. Among them, seven students participated in one of two focus groups. Overall, students accepted and favored the flipped learning strategy, and indicated that the method enhanced lecture content and their understanding of it. Factors associated with effective instruction included structured monitoring systems and motivational environments. Conclusion: The FLM requires sufficient preparation to facilitate student motivation and maximize learning outcomes. Choi, Heeseung · Kim, Jeongeun · Bang, Kyung-Sook, et al. comprehending the lectures [3,6]. In a study conducted with 360 undergraduate students in Taiwan, fewer than 6% of the students reported that they understood more than 90% of the lectures and fewer than 25...