Flexible substrate sensors for multiplex biomarker monitoring

Brennan, Desmond; Galvin, Paul

doi:10.1557/mrc.2018.134

Cited by 16 publications

(13 citation statements)

References 109 publications

(100 reference statements)

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“…In addition, microwave-based similar techniques have been developed and applied to determine electrolyte concentration in aqueous solutions such as NaCl, which play an essential role in living systems 16 – 18 , as well as chemical 19 , geological 20 , industrial processes 21 , and life science 22 , 23 . Biofluids such as blood, tears, sweat, urine, and saliva have been primary sources providing disease-specific biomarkers 24 , 25 . These biofluids are composed of metabolites and minerals (sodium, chloride, potassium, magnesium, zinc, iron, calcium, copper, phosphate).…”

Section: Introductionmentioning

confidence: 99%

Visualization of microwave near-field distribution in sodium chloride and glucose aqueous solutions by a thermo-elastic optical indicator microscope

Baghdasaryan

Babajanyan

Odabashyan

et al. 2021

Sci Rep

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In this study, a new optical method is presented to determine the concentrations of NaCl and glucose aqueous solutions by using a thermo-elastic optical indicator microscope. By measuring the microwave near-field distribution intensity, concentration changes of NaCl and glucose aqueous solutions were detected in the 0–100 mg/ml range, when exposed to microwave irradiation at 12 GHz frequency. Microwave near-field distribution intensity decreased as the NaCl or glucose concentration increased due to the changes of the absorption properties of aqueous solution. This method provides a novel approach for monitoring NaCl and glucose in biological liquids by using a CCD sensor capable of visualizing NaCl and glucose concentrations without scanning.

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Section: Introductionmentioning

confidence: 99%

Visualization of microwave near-field distribution in sodium chloride and glucose aqueous solutions by a thermo-elastic optical indicator microscope

Baghdasaryan

Babajanyan

Odabashyan

et al. 2021

Sci Rep

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“…Other important sweat analytes, such as the cytokines IL‐6 or the cortisol hormone, offer useful insights into inflammation and stress levels of individuals, respectively. [ 122 ] Like sweat, other body fluids such as saliva, tear, and interstitial fluid can also be used for the noninvasive monitoring of various biomarkers [ 123 ] (Figure 3b).…”

Section: Sweat Analytes and Monitoringmentioning

confidence: 99%

Energy Autonomous Sweat‐Based Wearable Systems

et al. 2021

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The continuous operation of wearable electronics demands reliable sources of energy, currently met through Li‐ion batteries and various energy harvesters. These solutions are being used out of necessity despite potential safety issues and unsustainable environmental impact. Safe and sustainable energy sources can boost the use of wearables systems in diverse applications such as health monitoring, prosthetics, and sports. In this regard, sweat‐ and sweat‐equivalent‐based studies have attracted tremendous attention through the demonstration of energy‐generating biofuel cells, promising power densities as high as 3.5 mW cm−2, storage using sweat‐electrolyte‐based supercapacitors with energy and power densities of 1.36 Wh kg−1 and 329.70 W kg−1, respectively, and sweat‐activated batteries with an impressive energy density of 67 Ah kg−1. A combination of these energy generating, and storage devices can lead to fully energy‐autonomous wearables capable of providing sustainable power in the µW to mW range, which is sufficient to operate both sensing and communication devices. Here, a comprehensive review covering these advances, addressing future challenges and potential solutions related to fully energy‐autonomous wearables is presented, with emphasis on sweat‐based energy storage and energy generation elements along with sweat‐based sensors as applications.

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“…Flexible substrates facilitate diagnostics, improving non-invasive health monitoring. A review of the available solutions of biosensors produced on flexible polymer substrates is described in [ 25 ]. Mathew et al described the possibility of using flexible, short-term disposable sensors on other polymer substrates to monitor health in real time, using physiological fluids such as saliva, sweat, and tear fluid (e.g., contact lenses for glucose monitoring) [ 26 ].…”

Section: Introductionmentioning

confidence: 99%

Prototype of a Textronic Sensor Created with a Physical Vacuum Deposition Process for Staphylococcus aureus Detection

Korzeniewska

Szczęsny

Lipiński

et al. 2020

Sensors

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Staphylococcus aureus is a bacterium which people have been in contact with for thousands of years. Its presence often leads to severe disorders of the respiratory and circulatory systems. The authors of this article present a prototype of a textronic sensor enabling the detection of this bacterium. This sensor was created using a process of physical vacuum deposition on a flexible textile substrate which can be implemented on clothing. With increasing numbers of bacterial colonies, changes in the sensor’s electrical parameters were observed. The sensor’s resistance reduced by 50% and the capacitance more than doubled within the first two days of starting bacterial cultures. Extensive changes in electrical parameters were observed at 100 Hz and 120 Hz of the measurement signal.

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Flexible substrate sensors for multiplex biomarker monitoring

Abstract: Abstract

Cited by 16 publications

References 109 publications

Visualization of microwave near-field distribution in sodium chloride and glucose aqueous solutions by a thermo-elastic optical indicator microscope

Visualization of microwave near-field distribution in sodium chloride and glucose aqueous solutions by a thermo-elastic optical indicator microscope

Energy Autonomous Sweat‐Based Wearable Systems

Prototype of a Textronic Sensor Created with a Physical Vacuum Deposition Process for Staphylococcus aureus Detection

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