Flaxseed Consumption May Reduce Blood Pressure: A Systematic Review and Meta-Analysis of Controlled Trials

Khalesi, Saman; Irwin, Christopher; Schubert, Matthew M.

doi:10.3945/jn.114.205302

Cited by 108 publications

(72 citation statements)

References 65 publications

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“…The risk of bias for each item is expressed simply as low risk, high risk or unclear risk of bias (27) . A previous analysis of fifty randomly selected meta-analyses of RCT (28) showed that 70 % applied the risk of bias assessment tool by the Cochrane collaboration, 10 % the Jadad scale (29) , 14 % reported no risk of bias/study quality/study limitations item, 4 % applied their own score and one study used the Rosendal scale (30) . A promising new evidence-synthesis method for intervention studies is network meta-analysis (NMA), which is an extension of pairwise meta-analysis that enables a simultaneous comparison of multiple interventions, forming a connected network while preserving the internal randomisation of individual trials.…”

Section: Specific Features Of Meta-analyses Of Randomised Controlled mentioning

confidence: 99%

Generating the evidence for risk reduction: a contribution to the future of food-based dietary guidelines

et al. 2018

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A major advantage of analyses on the food group level is that the results are better interpretable compared with nutrients or complex dietary patterns. Such results are also easier to transfer into recommendations on primary prevention of non-communicable diseases. As a consequence, food-based dietary guidelines (FBDG) are now the preferred approach to guide the population regarding their dietary habits. However, such guidelines should be based on a high grade of evidence as requested in many other areas of public health practice. The most straightforward approach to generate evidence is meta-analysing published data based on a careful definition of the research question. Explicit definitions of study questions should include participants, interventions/exposure, comparisons, outcomes and study design. Such type of meta-analyses should not only focus on categorical comparisons, but also on linear and non-linear dose-response associations. Risk of bias of the individual studies of the meta-analysis should be assessed, rated and the overall credibility of the results scored (e.g. using NutriGrade). Tools such as a measurement tool to assess systematic reviews or ROBIS are available to evaluate the methodological quality/risk of bias of meta-analyses. To further evaluate the complete picture of evidence, we propose conducting network meta-analyses (NMA) of intervention trials, mostly on intermediate disease markers. To rank food groups according to their impact, disability-adjusted life years can be used for the various clinical outcomes and the overall results can be compared across the food groups. For future FBDG, we recommend to implement evidence from pairwise and NMA and to quantify the health impact of diet-disease relationships.

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Section: Specific Features Of Meta-analyses Of Randomised Controlled mentioning

confidence: 99%

Generating the evidence for risk reduction: a contribution to the future of food-based dietary guidelines

et al. 2018

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“…Linseed, as this is high in dietary fiber, lignans and n-3 polyunsaturated fatty acids (PUFA) and there is some evidence for CVD-related benefits as per three reviews [32][33][34] and a recent trial [35]. More specifically, two meta-analyses report blood pressure reduction associated with linseed consumption [21,22]. Walnut (English walnut), as there is evidence that this food can benefit cardiovascular health as per a systematic review [36] and another recent review [37].…”

Section: Potential Ingredients Considered For Bread Designsmentioning

confidence: 99%

“…But other aspects of bread design can also be considered from a CVD prevention perspective given the evidence from systematic reviews around: increasing dietary fiber [19,20] and increasing linseed (flaxseed) intake which is high in alpha-linolenic acid [21,22]. Yet despite this evidence, our examination of the literature (as of June 2015) identified no optimization studies specifically relating to the design of heart healthy bread, and none concerning the design of low-cost healthier bread.…”

Section: Introductionmentioning

confidence: 99%

Designing low-cost “heart healthy bread”: optimization using linear programing and 15-country comparison

et al. 2016

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Background: Bread is an important component of the diet in many countries and provides needed nutrients but also typically too much of other nutrients e.g., sodium. We therefore aimed to use linear programing to determine the optimal design of low-cost "heart healthy bread" (HHB) and to compare the results with commercial breads in 15 countries. Methods: Optimization using linear programing focused on achieving set loaf prices (at NZ$1.5 and $3) and for a range of minimal sodium levels. Then within those constraints, levels of alpha-linolenic acid (ALA) were maximized, then dietary fiber, and then polyunsaturated fatty acids. Data from New Zealand (NZ) was used for the HHB designs and comparison nutrient and price data came from breads in 15 high-income countries. Results: The optimized loaf costing NZ$1.50 in ingredients (HHB$1.5) was superior to the commercial white loafs in three out of the eight heart health nutrient categories. The optimized loaf that was high in linseed and cost NZ$3 in ingredients (HHB$3), was nutritionally superior to the commercial loafs with seeds/nuts in six out of the eight heart health categories (i.e., in terms of sodium, potassium, fatty acid ratio and fiber). In terms of value-per-weight, a

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“…Ciśnienie skurczowe zmniejszyło się średnio o 10 mmHg, a ciśnienie rozkurczowe średnio o 7 mmHg. Wpływ na obniżenie ciśnienia tętniczego potwierdzono w metaanalizie [11]. Zaobserwowano także, że lepsze rezultaty, tj.…”

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“…Uzasadnione wydaje się wprowadzenie do pożywienia osób mających nadciśnienie siemienia lnianego codziennie w formie np. zalanych ciepłą wodą nasion [11].…”

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Superfoods: Perfect Addition or Unnecessery Supplement?

Ekiert¹,

Dochniak²

2015

Piel. Zdr. Publ.

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Nie od dziś wiadomo, że spożywana żywność ma ogromny wpływ na zdrowie człowieka. Już Hipokrates mawiał: "Niech pożywienie będzie lekarstwem" [1]. Większość ludzi zapomniała jednak jak ważną rolę w naszym życiu odgrywa żywienie. Coraz więcej osób cierpi z powodu chorób żywie-niowozależnych, takich jak: cukrzyca typu 2, choroby sercowo-naczyniowe, nowotwory, choroby przewodu pokarmowego. Są to schorzenia przewlekłe, które niewątpliwie zmniejszają jakoś życia, a ich leczenie generuje także koszty, dlatego należałoby więcej uwagi poświęcić zapobieganiu tym chorobom. W obecnych czasach stawia się na rozwój w wielu dziedzinach, takich jak technologia, A -koncepcja i projekt badania; B -gromadzenie i/lub zestawianie danych; C -analiza i interpretacja danych; D -napisanie artykułu; E -krytyczne zrecenzowanie artykułu; F -zatwierdzenie ostatecznej wersji artykułu Streszczenie W obecnych czasach, kiedy zmagamy się z plagą otyłości, a w rezultacie z cukrzycą typu 2, nowotworami żywie-niowozależnymi, chorobami sercowo-naczyniowymi, trudno nie łączyć tych problemów z nieprawidłowym ży -wieniem. Na skutek rozwoju handlu międzynarodowego i transportu na polskim rynku znacznie zwiększył się dostęp do produktów zagranicznych, egzotycznych roślin, owoców i warzyw. Dzięki tym działaniom mamy także dostęp do tzw. superfoods, czyli superżywności. Są to produkty roślinne, które były stosowane od wieków w róż-nych zakątkach świata jako panacea na dolegliwości chorobowe oraz jako podstawa lub składnik jadłospisów tamtejszych plemion. Charakteryzuje je duża zawartość składników odżywczych w małej masie produktu lub duża koncentracja takich składników, których w naszym pożywieniu często brakuje, np. kwasów tłuszczowych omega-3. Superfoods to nie tylko produkty zagraniczne. Wśród naszych rodzimych produktów również znajdziemy takie, które są bogactwem składników mineralnych i z powodzeniem możemy dodawać je do pożywienia. Celem pracy jest przedstawienie dostępnych na polskim rynku produktów superfoods, a także badań naukowych, które wskazują na ich potwierdzoną lub niepotwierdzoną skuteczność (Piel. Zdr. Publ. 2015, 5, 4, 401-408).Słowa kluczowe: dieta, opieka dietetyczna, prawidłowe żywienie. AbstractIt is well known that diet could have a huge impact on our health. Hippocrates said "Let food be medicine and medicine be food". Nowadays, we struggle with the plague of obesity and, in consequence, with diabetes mellitus 2, hormone-dependent cancers, and cardiovascular diseases. It is hard not to associate these problems with wrong eating. As a result of the development of international trade and transport in Poland, the number of overseas products, exotic plants, fruit and vegetables has increased. Because of it, we have access to superfoods. They are plant products that have been used for so many years in many quarters of the Earth as panacea for some illnesses or as basic food. Their main characteristic is that they have a lot of nutrients in a small mass or that they have a high concentration of these nutrients we do not have enough in ...

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Flaxseed Consumption May Reduce Blood Pressure: A Systematic Review and Meta-Analysis of Controlled Trials

Abstract: The present meta-analysis suggests that consumption of flaxseed may lower blood pressure slightly. The beneficial potential of flaxseed to reduce blood pressure (especially diastolic blood pressure) may be greater when it is consumed as a whole seed and for a duration of >12 wk.

Cited by 108 publications

References 65 publications

Generating the evidence for risk reduction: a contribution to the future of food-based dietary guidelines

Generating the evidence for risk reduction: a contribution to the future of food-based dietary guidelines

Designing low-cost “heart healthy bread”: optimization using linear programing and 15-country comparison

Superfoods: Perfect Addition or Unnecessery Supplement?

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