Flavonoids of Scutellaria immaculata Roots

Yuldashev, M. P.; Karimov, A. M.

doi:10.1007/s10600-005-0068-0

Cited by 10 publications

(15 citation statements)

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“…In this study we have recorded flavonoids 1 , 8 , 9 , 11 – 14 , 16 , 18 – 20 , 21 – 23 , 25 and 26 from aerial parts of S. immaculata for the first time (Tables 1 and 2, and Figures 2–4). The occurrence of flavonoids 14 , 25 , and 26 in S. immaculata is in agreement with the previously reported flavonoid profile [15,16] …”

Section: Resultssupporting

confidence: 92%

“…Flavonoids 1 – 7 , 9 – 14 and 16 – 27 from aerial parts and 3 – 8 , 10 – 16 and 18 – 27 from roots were identified in S. ramosissima for the first time (Figures 2–4). Flavonoids 14 , 21 and 25 had been isolated before from the aerial and roots from this plant [12–14,16] …”

Section: Resultsmentioning

confidence: 99%

“…S. immaculata has been studied previously and 17 flavonoids (chrysin‐7‐ O ‐glucuronide, scutellarein‐7‐ O ‐glucoside, apigenin‐7‐ O ‐glucoside, baicalein‐7‐ O ‐glucoside, norwogonin‐7‐ O ‐glucoside, oroxyloside, wogonoside, immaculoside, 5,2′‐dihydroxy‐6,7,6′‐trimethoxyflavanone, 5,2′‐dihydroxy‐6,7,8,6′‐tetramethoxyflavanone, chrysin, wogonin, apigenin, isoscutellarein, scutellarein, cosmosiin (apigenin‐7‐ O‐β ‐ d ‐glucopyranoside), and wogonin‐7‐O‐ β ‐ d ‐glucopyranoside) were identified; [15,16] and from S. ramosissima , chrysin 7‐ O‐β ‐ d ‐glucuronide, 2(S)‐2′,5,7‐trihydroxyflavanone 7‐ O ‐(Me β ‐ d ‐glucopyranosiduronate), 2(S)‐2′,5,7‐trihydroxyflavanone 7‐ O ‐(Et β ‐ d ‐glucopyranosiduronate), 5,2′‐dihydroxy‐7‐ O‐β ‐ d ‐glucopyranosylflavone, rivularin, 5,2′‐dihydroxy‐7‐ O ‐ β ‐ d ‐glucopyranosylflavanone, oroxylin A, wogonin, norwogonin, 5,2′,6′‐trihydroxy‐6,7,8‐trimethoxyflavone, and 5,6‐dihydroxy‐7,8‐dimethoxyflavone [12,13,23] . However, flavonoids have not been determined fully in S. immaculata and S. ramosissima .…”

Section: Discussionmentioning

confidence: 99%

“…are perennial shrubs that grow in Northern Tien Shan, Pamirs and Altay mountains (Central Asia). Chemical analysis of these plants indicate the presence of flavonoids [12–16] . Although, there are widespread reports about the anti‐tumour, antibacterial and antioxidant effects of some species of this genus, in‐vitro biological studies have not yet been conducted on S. immaculata and S. ramosissima .…”

Section: Introductionmentioning

confidence: 99%

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Flavonoids in Scutellaria immaculata and S. ramosissima (Lamiaceae) and their biological activity

Mamadalieva

Herrmann

El-Readi

et al. 2011

Journal of Pharmacy and Pharmacology

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Section: Resultssupporting

confidence: 92%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Flavonoids in Scutellaria immaculata and S. ramosissima (Lamiaceae) and their biological activity

Mamadalieva

Herrmann

El-Readi

et al. 2011

Journal of Pharmacy and Pharmacology

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“…[14][15][16] The HMBC spectrum showed long-range correlation between the anomeric proton signal H-1″ (δ H 5.07) and C-7 (δ C 163.34) supported the O-glycosidation at C-7. Based on these spectral data and by comparison with the literature data, 18 compound 3 was concluded to be luteolin-7-Oglucoside (cinaroside).…”

Section: Resultsmentioning

confidence: 84%

Chemical Constituents with Free-Radical- Scavenging Activity from the Leaves of Lantana montevidensis (Spreng.) Briq.

Makboul¹,

Attia²,

Farag³

et al. 2014

phcog J

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Background: Seventy percent aqueous methanolic extract of the leaves of Lantana montevidensis exhibited antibacterial, anti-inflammatory, anti-pyretic, antioxidant, and analgesic activities. Previous phytochemical study of the leaves led to the isolation of various flavones, pentacyclic triterpenoids, β-sitosterol and benzoic acid. Materials and Methods: The 70% aqueous methanolic extract of L. montevidensis (Spreng.) Briq. leaves was partitioned between water and n-hexane, ChCl 3 , etOac, and n-BuOh, successively. By using a series of different chromatographic techniques, the ChCl 3 and EtOAc extracts afforded nine compounds. The isolated compounds were identified by spectroscopic techniques and by comparison with literature values and/or authentic samples. the free radical scavenging activity of some of the isolated compounds was evaluated. Results: Hispidulin-7-O-glucurnoide methyl ester (1), hispidulin-7-O-glucoside (2), cinaroside (3), nepetin-7-O-glucoside (4) pectolinarigenin (5), apigenin (6), luteolin (7) in addition to salicylic acid (8) and β-sitosterol-3-O-glucoside (9) have been isolated. Compounds 1-4 are first report from the genus Lantana, whereas compounds 5, 8 and 9 are first report from this plant. The structures of these compounds were elucidated on the basis of spectral methods, including 2D nuclear magnetic resonance experiments, and confirmed by comparing with the literature data and/or authentic samples. Additionally, some of the isolated flavonoids exhibited free radical scavenging activity. Conclusion: L. montevidensis (Spreng.) Briq. cultivated in egypt is rich in biologically active ingredients.

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Traditional uses, chemical composition and biological activities ofSideritis raeseriBoiss. & Heldr.

Romanucci¹,

Fabio²,

D’Alonzo³

et al. 2016

J. Sci. Food Agric.

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Sideritis species have been used in folk medicine for their antimicrobial, antiulcerogenic, digestive and anti-inflammatory properties. Over the years, the phytochemistry of the genus Sideritis has been studied, and various terpenoids, sterols, coumarins and especially flavonoid aglycones and glycosides have been identified. In particular, species from the Balkan Peninsula have been studied and were found to be rich in flavonoids, with valuable antioxidant activity. In the folk medicine of the Balkan countries, Sideritis raeseri is used as a herbal tea in the treatment of inflammation, gastrointestinal disorders and coughs, and also as a tonic, whereas extracts are used as a component of dietary supplements for anaemia. Its dried inflorescences are used to prepare a beverage called 'mountain tea'. In light of the considerable interest generated in the chemistry, pharmacological properties and commercial value of S. raeseri Boiss. & Heldr., we review and summarise the available literature on these plants. The review details the chemical composition of the essential oil, its mineral and polyphenol contents, the naming of these plants and their physicochemical characterisation, and the nuclear magnetic resonance spectral data and biological properties associated with the plant extracts, with a focus on their potential chemotherapeutic applications. © 2016 Society of Chemical Industry.

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Flavonoids of Scutellaria immaculata Roots

Cited by 10 publications

References 4 publications

Flavonoids in Scutellaria immaculata and S. ramosissima (Lamiaceae) and their biological activity

Flavonoids in Scutellaria immaculata and S. ramosissima (Lamiaceae) and their biological activity

Chemical Constituents with Free-Radical- Scavenging Activity from the Leaves of Lantana montevidensis (Spreng.) Briq.

Traditional uses, chemical composition and biological activities ofSideritis raeseriBoiss. & Heldr.

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