Flavonoids and Phenolic Acids of Sage:  Influence of Some Agricultural Factors

Areias, Filipe; Valentão, Patrı́cia; Andrade, Paula B.; Ferreres, Federico; Seabra, Rosa M.

doi:10.1021/jf000440+

Cited by 82 publications

(52 citation statements)

References 8 publications

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“…Los intervalos de cantidades relativas y los compuestos identificados para las fracciones volátiles mostrados en la Tabla 3 no difirieron mucho de los valores reportados en otras investigaciones sobre extracción de S. officinalis con CO 2 supercrítico (Reverchon, et al, 1995;Aleksovski y Sovová, 2007;Ivanović, et al, 2009;Glisic, et al, 2010;Babovic, et al, 2010). La fracción no volátil de los extractos se sometió a un análisis por cromatografía líquida de alta eficiencia desarrollado para 11 compuestos fenólicos (ácidos caféico, p-cumárico, rosmarínico, carnósico y ursólico; apigenina, luteolina, quercetina, kaempferol, naringenina y pinocembrina), los cuales se han reportado como constituyentes del extracto de salvia o de tomillo (Areias, et al, 2000;Lu y Foo, 2001). Solo se detectaron los ácidos carnósico (ACA) y ursólico (AUR), probablemente porque estos terpenos no muy polares poseen mayor solubilidad en CO 2 supercrítico que en agua (Herrero, et al, 2010).…”

Section: Caracterización Cromatográficaunclassified

Optimización de la extracción de antioxidantes de Salvia officinalis L. con CO2 supercrítico

Martı́nez¹,

Ruiz²,

Arias³

et al. 2014

Rev. Acad. Colomb. Cienc. Ex. Fis. Nat.

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ResumenSe aplicó un diseño factorial fraccionado 2 7-2 para seleccionar las variables con mayor efecto sobre la capacidad antioxidante, el contenido de fenoles y el rendimiento de la extracción utilizando CO 2 supercrítico como solvente sobre hojas y tallos de Salvia officinalis L. El tiempo de extracción, el flujo de CO 2 , la presión de la cámara de extracción y la temperatura de separación se modificaron según el procedimiento simplex para hallar empíricamente las condiciones que produjeran extractos de salvia con el valor más alto de la combinación lineal de rendimiento de extracción, capacidad antioxidante y contenido total de fenoles.Palabras clave: Salvia officinalis, supercrítico, optimización simplex, ácido carnósico. Optimization of the extraction of Salvia officinalis L. antioxidants with supercritical CO 2 AbstractA 2 7-2 fractional factorial design was used to select the variables with the greatest effect on the antioxidant capacity, the total phenolic content and the extraction yield using supercritical carbon dioxide as a solvent on Salvia officinalis L. leaves and stems. The extraction time, the CO 2 flow, the extraction chamber pressure and the collector temperature were modified according to the simplex method in order to empirically find the conditions resulting in salvia extracts with the highest value of the linear combination of extraction yield, antioxidant capacity and total phenolic content.Key words: Salvia officinalis, supercritical, simplex optimization, carnosic acid. Ciencias naturales IntroducciónLa capacidad antioxidante es una propiedad biológica de gran interés para las diversas aplicaciones de las plantas aromáticas. En la salvia (Salvia officinalis) se ha reconocido desde hace mucho tiempo esta propiedad que, junto a su poder microbicida, ha permitido usarla con éxito como preservante de cárnicos y otros alimentos (Meyer, et al., 2002). De la salvia y de otras muchas plantas aromáticas y medicinales se utilizan sus aceites esenciales, sus extractos o sus partes (hojas, flores, raíces) como ingredientes de diversas preparaciones y productos comerciales para el consumo humano. En la búsqueda de una explicación molecular de la actividad biológica de la salvia se ha demostrado que en sus metabolitos secundarios se encuentran varias sustancias que poseen alta capacidad antioxidante, tales como los ácidos fenólicos rosmarínico, salvianólico y ursólico, los flavonoides luteolina y salvicoumarina y los diterpenos fenólicos ácido carnósico, carnosol y rosmanol (Wang, et al., 1998;Lu, et al., 1999a;Lu, et al., 1999b;Lu, et al., 2000;Lu, et al., 2001). Entre estos, los ácidos rosmarínico y carnósico presentan la mayor capacidad antioxidante, superior a la del 2,6-di-terc-butil-p-cresol (BHT) y la del terc-butil-4-metoxifenol (BHA), antioxidantes de amplio uso en la industria (Sebranek, et al., 2005).En la elaboración de productos farmacéuticos y alimenticios, o en otras aplicaciones para consumo humano, es importante la eliminación de los residuos de solventes orgánicos utilizados en el...

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Section: Caracterización Cromatográficaunclassified

Optimización de la extracción de antioxidantes de Salvia officinalis L. con CO2 supercrítico

Martı́nez¹,

Ruiz²,

Arias³

et al. 2014

Rev. Acad. Colomb. Cienc. Ex. Fis. Nat.

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“…Tabulated data on food composition generally include only mean values on fat composition, but there are several factors such as the cultivar, geographical origin, and agricultural practices that can affect compositional values (16,17).…”

Section: Introductionmentioning

confidence: 99%

Determination of Sterol and Fatty Acid Compositions, Oxidative Stability, and Nutritional Value of Six Walnut (Juglans regia L.) Cultivars Grown in Portugal

Amaral

Casal

Pereira

et al. 2003

J. Agric. Food Chem.

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247

155

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Six cultivars (Franquette, Marbot, Mayette, Mellanaise, Lara, and Parisienne) of walnuts (Juglans regia L.) were collected during the 2001 crop, from Braganç a, Portugal. Chemical composition, including moisture, total oil content, crude protein, ash, carbohydrates, and nutritional value, was evaluated. Fat was the predominant component, ranging from 62.3 to 66.5%. Total oil was extracted and analyzed for fatty acids, sterols, oxidative stability, and peroxide value. Fatty acids and sterols were determined by gas-liquid chromatography coupled to a flame ionization detector. Eighteen fatty acids were quantified. Polyunsaturated fatty acids and, in particular, linoleic acid were predominant. -Sitosterol, ∆ 5 -avenasterol, and campesterol were the major sterols found. Differences were observed among the studied cultivars, especially in peroxide values and in the sterol profile.

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“…For instance sage plants cultivated North of Portugal contained rosmarinic acid as the major compound of the total phenolics (Areias et al, 2000). The presence of rosmarinic acid was also reported in field-grown as well as various in vitro cultures of S. officinalis plants originating in Poland (Grzegorczyk et al, 2007).…”

Section: Content Of Essential Oils and Rosmarinic Acidmentioning

confidence: 83%

Determination of Essential Oil Bioactive Components and Rosmarinic Acid of Salvia officinalis Cultivated under Different Intra-row Spacing

Darwish¹,

AL-Dein²,

Amamneh

et al. 2013

Not Sci Biol

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Salvia officinalis, known also as sage, is a medicinal plant belonging to the Lamiaceae family that spreads all over the word in several countries. The demand for the raw material and extracts of this plant is increasing due to its numerous applications in pharmacy, food and herbal tea production. The present study investigated for the first time the effect of 15, 30 and 45 cm intra-row spacing (plant density) on the main constituents of sage essential oils and rosmarinic acid content. The highest content of essential oils (2.7%) and rosmarinic acid (2.0%) were obtained in plants grown using 15 cm planting space. Likewise, close spacing resulted also in a substantial content of 1,8-cineole (47-50%, GC/FID; 55-60%, GC/MS). This work indicated that 1,8-cineole chemotype was a dominant character of cultivated S. officinalis in south of Jordan. In general, the percent of α-thujone in essential oil was not affected by intra-row spacing. However, the percent of β-thujone decreased from (2-3%, GC/MS) in plants grown using 15 cm intra-row spacing to (1-2%, GC/MS) in plants grown using 30 and 45 cm intra-row spacing. The highest content of α-and β-pinene was recorded in plants grown using 45 cm planting space (8-10%, GC/FID; 5-6% GC/MS). Based on GC/MS, camphor compound was enriched (9-10%) in sage plants grown under 15 cm spacing and greater than in plants grown under 30 (6-7%) or 45 cm (5-6%) spacing. The results make the potential use of sage extracts in the treatment of some human disorders or illness an area of further research.

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Flavonoids and Phenolic Acids of Sage: Influence of Some Agricultural Factors

Cited by 82 publications

References 8 publications

Optimización de la extracción de antioxidantes de Salvia officinalis L. con CO2 supercrítico

Optimización de la extracción de antioxidantes de Salvia officinalis L. con CO2 supercrítico

Determination of Sterol and Fatty Acid Compositions, Oxidative Stability, and Nutritional Value of Six Walnut (Juglans regia L.) Cultivars Grown in Portugal

Determination of Essential Oil Bioactive Components and Rosmarinic Acid of Salvia officinalis Cultivated under Different Intra-row Spacing

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