Flavonoid glycosides and triterpenoids from Atractylis flava

Acylated flavonol glycosides from the flower of Elaeagnus angustifolia L.

“…The interglycosidic linkage of the disaccharide moiety was also determined from HMBC data. Correlations from H-1 of glc to the downfield-shifted C-2 of gal indicated that the gal residue was 2-O-linked to glc (Chabani et al, 2013). The down field shifted methylene protons glc-6 (d H 4.36 and 4.42) and the correlation observed in the HMBC spectrum between these protons and the ester carbonyl d C 169.0 indicated the attachment of the E-coumaroyl group to C-6 of glc.…”

“…Complete the assignment of the remaining resonances of the aglycone in the 13 C NMR spectrum of 1 was achieved by analysis of the HSQC and HMBC data , which confirmed the presence of isorhamnetin (3,5,7,4 0 -tetrahydroxy-3 0 -methoxyflavone). A full list of the corresponding assignments is given in Table 1 (Chabani et al, 2013;Fang et al, 2013;Prescott et al, 2013). The COSY and 1 H NMR spectra of 1 showed also four aromatic protons at d H 6.71 (2H, d, J = 8.6 Hz), 7.18 (2H, d, J = 8.6 Hz) and two olefinic protons at d H 6.05 (d, J = 15.9 Hz) and 7.39 (d, J = 15.9 Hz).…”

“…The b-D-galactopyranose was characterized by the large coupling constants J H1,H2 and J H2,H3 and the small coupling constant J H3,H4 (3.5 Hz) whereas the b-D-glucopyranose was characterized by large coupling constants (J H1,H2 , J H2,H3 , J H3,H4 , J H4,H5 P 7.6 Hz) as summarized in Table 1. The set of chemical shift values for the 13 C resonances corresponding to glucose suggested that this residue occupied a terminal position on a branched glycosidic chain whereas the down field signal of C-2 of galactose (82.0 ppm) suggested the interglycosidic linkage (Chabani et al, 2013) (Table 1). A correlation between H-1 of gal and d C 135.1 in the HMBC spectrum of 1 defined C-3 of isorhamnetin as the site of O-glycosylation.…”

Anti-Inflammatory, Anti-pyretic and Acute Toxicity Effects of n-Butanol Extract of Atractylis flava Desf in Rats

“…Furthermore, the presence of a tiliroside, narcissin, vicenin 3, ladaneine and schaftoside were detected in the n-butanol extract. 8,9 Flavonoids have been demonstrated that they are able to inhibit a series of enzymes, which are activated in the course of the inflammatory process. 26 Also, flavonoid such as vicenin-2, Tiliroside, Schaftoside, have been recognized as potent inhibitors of pro-inflammatory mediators in different studies.…”

“…8 Furthermore, the presence of a tiliroside, narcissin, vicenin3, ladaneine and schaftoside was confirmed in the n-butanol extract of this plant. 8,9 However, no data were found regarding the pharmacological evaluation of the plant. The aim of the present study is to evaluate the antiinflammatory and antipyretic properties of the n-butanol extract of the whole plant Atractylis flava Desf (BEAF).…”