2010
DOI: 10.1111/j.1365-2125.2010.03651.x
|View full text |Cite
|
Sign up to set email alerts
|

Fixed drug eruption with ornidazole having cross‐sensitivity to secnidazole but not to other nitro‐imidazole compounds: a case report

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

0
33
0
3

Year Published

2010
2010
2021
2021

Publication Types

Select...
5
2

Relationship

0
7

Authors

Journals

citations
Cited by 32 publications
(36 citation statements)
references
References 8 publications
0
33
0
3
Order By: Relevance
“…[3] Cross sensitivity tends to occur in other drugs similar in structure to the causative agent. [15] FDE due to thiacetazone was observed in one patient.Mani et al [16] Reported that thiacetazone was the most common antimicrobial drug to cause eruptions. The time latency between application and reaction ranged from ½ hour to 10 hours with a mean of 2.36 hours.…”
Section: Resultsmentioning
confidence: 93%
“…[3] Cross sensitivity tends to occur in other drugs similar in structure to the causative agent. [15] FDE due to thiacetazone was observed in one patient.Mani et al [16] Reported that thiacetazone was the most common antimicrobial drug to cause eruptions. The time latency between application and reaction ranged from ½ hour to 10 hours with a mean of 2.36 hours.…”
Section: Resultsmentioning
confidence: 93%
“…FDE due to ornidazole in previously documented three cases had involved lips, chest and antero-lateral aspect of thigh. [4][5][6] Our case described here is unique as it involved the intra-oral site of hard palate, a site never associated with FDE, resulting due to use of ornidazole.…”
Section: Discussionmentioning
confidence: 88%
“…The drug is postulated to be acting as a hapten that binds to basal keratinocytes and resulting in the release of lymphokines and antibodies that in turn damage the basal cell layer. 4 On drug intake CD8+ are reactivated to release IFN and cytotoxic granules into the local microenvironment. Mast cells are also believed to contribute to activation of intraepidermal CD8+ cells through the induction of cell adhesion molecules.…”
Section: Discussionmentioning
confidence: 99%
See 2 more Smart Citations