Five‐year experience in the treatment of alopecia areata with DPC

Abstract

Diphencyprone is an effective and safe treatment of extensive AA. A long period of therapy is needed and will increase the percentage of responders especially in alopecia totalis and universalis. Maintenance therapy is recommended to reduce the risk of relapse.

Retrospective review of diphencyprone in the treatment of alopecia areata

“…Patient and treatment variables are reported as being relevant in response to DCP . The variables assessed in this study included baseline AA severity, disease duration, atopy, nail dystrophy and hair growth response.…”

Late‐onset alopecia areata: A retrospective study of 73 patients from Taiwan

“…However, severe AA in the elderly may pose a therapeutic challenge due to the other coexisting systemic diseases. The efficacy of topical immunotherapy such as DPCP in aged patients is poorly clarified in the literature 20,21 . The clinical efficacy of topical DPCP seems to correlate with the baseline extent of AA but not the age of onset 21 .…”

Methotrexate in alopecia areata: A report of three cases

“…Topical immunotherapy with diphencyprone,[4] pulses of systemic corticosteroids,[5] psoralen and ultraviolet A,[6] and 308-nm excimer laser[7] have been reported as effective in pediatric patients. In addition, in the last decade, MTX has been proposed as an alternative and safe option for severe cases in AA in both adults and children.…”