Five‐country manikin study found that neonatologists preferred using the LISAcath rather than the Angiocath for less invasive surfactant administration

Abstract

AimLess invasive surfactant administration (LISA) has been shown to decrease the risk of death and bronchopulmonary dysplasia in preterm neonates. The LISAcath is the first catheter to be specifically developed for LISA, and we compared the clinical impressions of neonatologists using the LISAcath and the commonly used Angiocath in a simulated setting.MethodsThis was a multinational, multicentre study, conducted in October 2016, which involved 39 neonatologists who were recruited by employees of the sponsor from large, well‐recognised neonatal intensive care units across Europe. LISA was not the standard of care in these units in Austria, Belgium, Poland, Spain and the United Kingdom at the time of the study. After training, participants simulated LISA on a neonatal manikin, once with the LISAcath and once with Angiocath, then answered a 10‐item questionnaire.ResultsThe responses to nine of 10 questions showed that 67‐95% of the respondents preferred the LISAcath to the Angiocath, with most of the remainder indicating no preference. The only exception was the luer connection question, with two‐thirds expressing no preference. The LISAcath was considered potentially safer by 33 of 39 participants, with no votes for the Angiocath.ConclusionOverall, neonatologists preferred using the LISAcath rather than the Angiocath on a neonatal manikin.

Minimally Invasive Surfactant Therapy: An Analytical Report of Our Prospective Dubai Cohort

“…We have earlier reported that this improvised MIST equivalent of the semirigid catheter technique (the prototype is the LISA catheter) is technically simpler to adapt in clinical practice [15]. This observation is in conformity with earlier reports from Europe [23][24].…”

“…As LISA catheter may not be readily available in all units, we later performed an improvised MIST procedure using the smallest size ETT 2.0, whose inner diameter is equivalent to 8 Fr infant feeding tube and instilled surfactant directly from a syringe attached to the hub of the ETT. Infant feeding tubes are usually made of polyurethane material that is much more flexible and hence difficult to guide into the trachea in contradistinction to the poly vinyl chloride material that is in ETT [23][24]. We have earlier reported that this improvised MIST equivalent of the semirigid catheter technique (the prototype is the LISA catheter) is technically simpler to adapt in clinical practice [15].…”

Less invasive surfactant administration (LISA): chances and limitations

“…Routine oral intubation is more common in other parts of the world, so that the use of a stiff vascular catheter was described by Peter Dargaville et al 11 as the so-called Hobart method (minimally invasive surfactant therapy (MIST)) in 2011. Straight (LISAcath)12 or stiff catheters with an angulated tip (Surfcath) have been designed especially for the purpose of LISA via the oral route. Special introducers13 (Neocath) and devices to guide the catheter when video laryngoscopy is being used have recently been developed.…”

Implementation of less invasive surfactant administration in clinical practice—Experience of a mid-sized country

“…The options included LISAcath or vascular catheters, which had been used in almost 90% of infants. LISAcath was previously shown to be the most commonly used catheter in a recent survey from the UK [17,18]. Semirigid vascular catheters are also preferred by Spanish doctors [10].…”