Fish‐elastin Hydrolysate: Development and Impact on the Skin and Blood Vessels

Sugawara, Eri; Nakaba, Misako; Shigemura, Yasutaka; Yamada, Michio; Satô, Kenji

doi:10.1002/9781118375082.ch23

Cited by 7 publications

(11 citation statements)

References 34 publications

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“…Elastin is an important protein component of the extracellular matrix in numerous tissues that require elasticity to perform their functions [35]. It is part of the core architecture that supports cell growth and, consequently, is in direct contact with multiple cell types.…”

Section: Elastinmentioning

confidence: 99%

Trends in biopolymer science applied to cosmetics

Mendoza‐Muñoz

Leyva-Gómez

Piñón-Segundo

et al. 2023

Intern J of Cosmetic Sci

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The term biopolymer refers to materials obtained by chemically modifying natural biological substances or producing them through biotechnological processes. They are biodegradable, biocompatible and non‐toxic. Due to these advantages, biopolymers have wide applications in conventional cosmetics and new trends and have emerged as essential ingredients that function as rheological modifiers, emulsifiers, film‐formers, moisturizers, hydrators, antimicrobials and, more recently, materials with metabolic activity on skin. Developing approaches that exploit these features is a challenge for formulating skin, hair and oral care products and dermatological formulations. This article presents an overview of the use of the principal biopolymers used in cosmetic formulations and describes their sources, recently derived structures, novel applications and safety aspects of the use of these molecules.

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Section: Elastinmentioning

confidence: 99%

Trends in biopolymer science applied to cosmetics

Mendoza‐Muñoz

Leyva-Gómez

Piñón-Segundo

et al. 2023

Intern J of Cosmetic Sci

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“…In this regard, it is suggested that ingestion of elastin hydrolysate might improve the condition of the skin. Recent consumer preference for marine products, the availability and relatively low cost coupled with its demonstrated presence of elastin peptides and biological potency of skipjack (Shiratsuchi, Nakaba, Shigemura, Yamada, & Sato, 2013) makes it a good candidate for further exploring the mechanism of photoaging. We hypothesized that skipjack elastin hydrolysate small peptides have free radicals scavenging ability.…”

Section: Introductionmentioning

confidence: 99%

Skipjack (Katsuwonus pelamis) elastin hydrolysate‐derived peptides attenuate UVA irradiation‐induced cell damage in human HaCaT keratinocytes

Amakye

Liu

Yao³

et al. 2021

Food Frontiers

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We aimed to identify skipjack elastin hydrolysate‐derived peptides, and explore its mechanism of photoprotection against ultraviolet A (UVA) induced skin damage. Two peptides, TGVLTVM (peptide A) and NHIINGW (peptide B), were successfully identified using Sephadex G‐15, analyzed and detected using LC‐MS/MS fitted with electrospray ionization (ESI‐MS/MS), and further synthesized using the Fmoc strategy. A UVA radiation‐induced damage cell model of Human keratinocytes cell line (HaCaT) was established and applied. We found that both peptides significantly reduced reactive oxygen species (ROS) generation, reversed mitochondrial membrane potential (MMP) by 12.40%–13.13% and 10.80%–12.90% and reduced cell apoptosis by 3.43%–6.44%, and 4.56%–6.03% for peptide A and B, respectively, compared to the UVA model group. In conclusion, peptides TGVLTVM and NHIINGW protected against UVA‐induced photoaging through the attenuation of oxidative stress, thus both peptides might be useful as promising ingredients in sunscreens or antiaging cosmetic products.

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“…Collagen gives tissue mechanical strength, while elastin provides elasticity and plays a significant role in tissue development [3]. Only a few tissues, such as ligament and blood vessels are rich in elastin [4].…”

Section: Introductionmentioning

confidence: 99%

“…After enzymatic breakdown collagen and elastin form low molecular peptides, which are rapidly absorbed from the gastrointestinal tract and may act as signalling molecules, thereby stimulating anabolic processes in the organism [2,3,6]. The peptides with low molecular weight originated from collagen and elastin reveal the high biological activity [7,8].…”

Section: Introductionmentioning

confidence: 99%

“…High amounts of Gly and Pro residues play an important role in the biological activity of collagen [12]. Pro-Gly dipeptide originated from Skipjack-elastin hydrolysate enhances the elastin synthesis by human dermal fibroblast and the growth of human umbilical vein endothelial cells [3]. The biological activity of released peptides depends on the enzyme specificity and proteolysis conditions [12,13].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Antioxidant and Antihypertensive Activity of Collagen and Elastin Hydrolysate at Different Molecular Weights

Munkhuu¹,

Erdene²,

Bayarsukh³

et al. 2021

Atlantis Highlights in Chemistry and Pharmaceutical Sciences

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The angiotensin-converting enzyme (ACE) inhibitory activity and antioxidant property of collagen and elastin hydrolysates, and their peptide fractions (< 5 kDa, 5-10 kDa, 10-100 kDa) were compared. The bovine raw-hide and paddywhack (Ligamentum nuchae) were used for the preparation of collagen and elastin hydrolysates, respectively. Unfractionated collagen and elastin hydrolysates (4 mg/mL) could reduce ACE activity by 61% and 58%. As a result of fractionation, ACE inhibitory activity of collagen hydrolysate was increased up to 85%, while this effect was not observed on elastin hydrolysate. Elastin hydrolysate showed intense radical scavenging abilities through 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-Azinobis-(3-Ethylbenzthiazolin-6-Sulfonic Acid (ABTS) assay. The collagen hydrolysate obtained from the bovine rawhide has more perspective for the bioactive food additive having ACEI activity in comparison with the elastin hydrolysate.

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Fish‐elastin Hydrolysate: Development and Impact on the Skin and Blood Vessels

Cited by 7 publications

References 34 publications

Trends in biopolymer science applied to cosmetics

Trends in biopolymer science applied to cosmetics

Skipjack (Katsuwonus pelamis) elastin hydrolysate‐derived peptides attenuate UVA irradiation‐induced cell damage in human HaCaT keratinocytes

Antioxidant and Antihypertensive Activity of Collagen and Elastin Hydrolysate at Different Molecular Weights

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