First Report of the Plasmid-Mediated Colistin Resistance Genemcr-1inEscherichia coliST405 Isolated from Wildlife in Bejaia, Algeria

Bachiri, Taous; Lalaoui, Rym; Bakour, Sofiane; Allouache, Meriem; Belkebla, Nadia; Rolain, Jean‐Marc; Touati, Abdelaziz

doi:10.1089/mdr.2017.0026

Cited by 49 publications

(32 citation statements)

References 45 publications

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“…MDR was identified in 42 out of 59 AMR isolates (71.2%). The prevalence of MDR isolates from small mammals in Hanoi was higher than those observed in Vancouver, Canada birds and rodents were concerned as potential carriers and/ or spreaders of colistin-resistant E. coli [1,2,4,13,34,45,47]. Our data revealed that urban rodents could be a carrier and spreader of colistin-resistant E. coli ( Table 6).…”

Section: Discussionmentioning

confidence: 54%

Antibiotic-resistant Escherichia coli isolated from urban rodents in Hanoi, Vietnam

Huy

Koizumi

Ung

et al. 2020

The Journal of Veterinary Medical Science

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Antimicrobial resistance (AMR) is a global public health concern for both clinical and veterinary medicine. Rodent feces are one of the major infectious sources of zoonotic pathogens including AMR bacteria. So far, there are limited studies reported focused on Escherichia coli isolated in rodent feces from rural and suburban areas in Vietnam. In this study, we investigated the prevalence of antimicrobial resistance in E. coli isolated from feces samples of 144 urban rodents caught in Hanoi, Vietnam. A total of 59 AMR E. coli was isolated from urban rodents of which 42 were multidrug-resistant (MDR) isolates (resistance to at least three classes of antimicrobial agents), four were extended-spectrum β-lactamase (ESBL) producing isolates and five were colistin-resistant isolates. The highest prevalence of the resistance was against

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Section: Discussionmentioning

confidence: 54%

Antibiotic-resistant Escherichia coli isolated from urban rodents in Hanoi, Vietnam

Huy

Koizumi

Ung

et al. 2020

The Journal of Veterinary Medical Science

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“…In a clinical study from King Abdulaziz Medical City (KAMC) in Riyadh (Alghoribi et al, 2015), six ST405 E. coli harboring bla CTX-M were detected in UTI and ST405 (P ≤ 0.02) were significantly associated with ESBL production. ST405 extended-spectrum β-lactamase-producing E. coli (ESBL-EC) was also detected in animals, in which one ST405 ESBL-EC was screened in barbary macaques (Macaca sylvanus) in Algeria, notably, it held the mcr-1, bla TEM−1 , and qnrB19 genes and bla CTX-M-15 (Bachiri et al, 2017). We observed a similar pattern and a UTI25 (ST405 ESBL-EC) isolate harbored mcr-1, bla TEM , qnrB, and bla CTX-M−64 .…”

Section: Discussionmentioning

confidence: 99%

Increasing Prevalence of ESBL-Producing Multidrug Resistance Escherichia coli From Diseased Pets in Beijing, China From 2012 to 2017

et al. 2019

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We investigated antimicrobial resistance trends and characteristics of ESBL-producing Escherichia coli isolates from pets and whether this correlates with antibiotic usage in the clinic. Clinical samples containing E. coli from diseased cats and dogs were screened for antibiotic sensitivity and associated genotypic features. We identified 127 E. coli isolates from 1886 samples from dogs (n = 1565) and cats (n = 321) with the majority from urinary tract infections (n = 108, 85%). High rates of resistance were observed for β-lactams and fluoroquinolones and resistance to > 3 antibiotic classes (MDR) increased from 67% in 2012 to 75% in 2017 (P < 0.0001). This was especially true for strains resistant to 6-9 antibiotics that increased from 26.67 to 60.71%. Increased rates in β-lactam use for clinical treatment accompanied these increasing resistance rates. Accordingly, the most frequently encountered subtypes were bla CTX-M (n = 44, 34.65%), bla CTX-M-65 (n = 19) and bla CTX-M-15 (n = 18) and qnrB (n = 119, 93.70%). The bla CTX-M-isolates possessed 36 unique pulsed field electrophoretic types (PFGEs) and 28 different sequence types (STs) in ST405 (7, 15.9%), ST131 (3, 6.8%), ST73, ST101, ST372, and ST827 (2, 4.5% each) were the most prevalent. This data demonstrated a high level of diversity for the bla CTX-M-positive E. coli isolates. Additionally, bla NDM-5 was detected in three isolates (n = 3, 2.36%), comprised of two ST101 and one ST405 isolates, and mcr-1 was also observed in three colistin-resistant E. coli with three different STs (ST6316, ST405, and ST46). Our study demonstrates an increasing trend in MDR and ESBL-producing E. coli and this correlated with β-lactam antibiotic usage for treatment of these animals. This data indicates that there is significant risk for the spread of resistant bacteria from pets to humans and antibiotic use for pets should be more strictly regulated.

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“…[Color figure can be viewed at wileyonlinelibrary.com] ST162 E. coli carrying mcr-1 was also isolated from a wild Black vulture in Spain (Oteo et al, 2018) and two mcr-1positive E. coli isolated from imported reptiles (Asian grass lizards) in Germany (Unger et al, 2017). In Africa, a Macaca sylvanus, a primate, was found to be colonized with a ST405 E. coli carrying the mcr-1 gene in Algeria (Table 1) (Bachiri et al, 2018).…”

Section: Prevalence Of Mcr Genes In Animals and Animalderived Food Prmentioning

confidence: 99%

Farm animals and aquaculture: significant reservoirs of mobile colistin resistance genes

Shen

Zhang

Schwarz

et al. 2020

Environmental Microbiology

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Summary Colistin resistance has attracted substantial attention after colistin was considered as a last‐resort drug for the treatment of infections caused by carbapenem‐resistant and/or multidrug‐resistant (MDR) Gram‐negative bacteria in clinical settings. However, with the discovery of highly mobile colistin resistance (mcr) genes, colistin resistance has become an increasingly urgent issue worldwide. Despite many reviews, which summarized the prevalence, mechanisms, and structures of these genes in bacteria of human and animal origin, studies on the prevalence of mobile colistin resistance genes in aquaculture and their transmission between animals and humans remain scarce. Herein, we review recent reports on the prevalence of colistin resistance genes in animals, especially wildlife and aquaculture, and their possibility of transmission to humans via the food chain. This review also gives some insights into the routine surveillance, changing policy and replacement of polymyxins by polymyxin derivatives, molecular inhibitors, and traditional Chinese medicine to tackle colistin resistance.

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First Report of the Plasmid-Mediated Colistin Resistance Genemcr-1inEscherichia coliST405 Isolated from Wildlife in Bejaia, Algeria

Abstract: In this study, we report the detection of mcr-1 gene producing E. coli from wild animals.

Cited by 49 publications

References 45 publications

Antibiotic-resistant <i>Escherichia coli</i> isolated from urban rodents in Hanoi, Vietnam

Antibiotic-resistant <i>Escherichia coli</i> isolated from urban rodents in Hanoi, Vietnam

Increasing Prevalence of ESBL-Producing Multidrug Resistance Escherichia coli From Diseased Pets in Beijing, China From 2012 to 2017

Farm animals and aquaculture: significant reservoirs of mobile colistin resistance genes

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