First Presentation of Lung Adenocarcinoma as a Subungual Metastasis

Abstract

Subungual metastasis as a presenting feature of lung adenocarcinoma is rare and may be confused with a benign inflammatory disorder of the nail unit with subsequent diagnostic and management delay. We discuss the case of a 46-year-old man with a subungual metastasis as a presenting feature of lung adenocarcinoma.

Subungual metastasis: expanding the spectrum

“…Dudley et al reported erythema with features of seborrheic dermatitis and LE associated with 5 fluorouracil in 1987. 2 A similar SA distribution has been reported in a related connective-tissue disorder: dermatomyositis (DM), especially in Japan. 3 A seborrheic pattern of DM has been described in 10 of 14 adult patients with DM and facial fold erythema.…”

Subungual Metastasis from Ovarian Cancer: Case Report and Brief Review of the Literature

“…There are 2 different types of presentations, as a redviolaceous subungual mass, associated with a distorted nail plate and bleeding, as in our case, or with a globally enlarged erythematous distal digit, involving the distal phalanx [4][5][6][7][8][9][10]. Periungual masses are usually the consequence of the local enlargement of the metastasis from the subungual initial localization.…”