First molecular identification of Echinococcus vogeli and Echinococcus granulosus (sensu stricto) G1 revealed in feces of domestic dogs (Canis familiaris) from Acre, Brazil

Abstract

Background Echinococcus granulosus (sensu lato) (s.l.) and Echinococcus vogeli are causative agents of chronic zoonotic diseases such as cystic and polycystic echinococcosis, respectively. In Brazil, polycystic echinococcosis has a restricted geographical distribution in the North Region, while cystic echinococcosis is observed in the South Region. Domestic dogs (Canis familiaris) fed with raw viscera represent a risk factor for E. granulosus (s.l.) infection in the South Region. Although this practice is frequent, it remains unclear whether domestic dogs are infected with E. vogeli in the state of Acre, located in the Amazon basin in the North Region of Brazil. The aim of this study was to investigate this gap in the polycystic echinococcosis epidemiology.MethodsSixty-five fecal samples were collected from the ground in five municipalities (Sena Madureira, n = 14; Rio Branco, n = 06; Bujari, n = 06; Xapuri, n = 30; and Epitaciolândia, n = 09) located in the state of Acre, northern Brazil. The samples were screened for parasites by copro-PCR using the cox1 gene associated with automated sequencing.Results Echinococcus vogeli was molecularly confirmed in a sample from Sena Madureira and E. granulosus (sensu stricto) (s.s.) (G1) in a sample from Rio Branco.ConclusionsThese findings indicate that molecular assays are useful in typing Echinococcus taxa from fecal samples of dogs in northern Brazil. The present study is the first molecular record of E. vogeli in domestic dogs found in the state of Acre, reinforcing their role as a source of infection for humans. Because E. granulosus (s.s.) (G1) was detected for the first time in the North Region, from the epidemiological standpoint this finding is highly relevant, because it expands the known geographical distribution, which was previously restricted to the South Region of Brazil.

Intestinal transcriptomes in Kazakh sheep with different haplotypes after experimentalEchinococcus granulosusinfection

“…However, in definitive hosts like dogs, adult parasites develop from the protoscolex in the intestine. In domestic animals, especially in sheep, which appear to be highly susceptible to infection [ 38 ], CE causes considerable health problems and thereby significantly affects the income of herders [ 32 ].…”

The Molecular Epidemiology of Echinococcus Infections

“…Although both E. oligarthra and E. vogeli have been reported to infect humans [ 3 ], their zoonotic significance is unknown. A recent report from Brazil [ 25 ] demonstrated that molecular screening of dog faeces is a useful tool for determining the potential public health significance of E. vogeli infections in domestic dogs.…”

Monitoramento E Ações Para O Controle De Agentes Zoonóticos Em Comunidades Adjacentes a Uma Floresta Urbana No Município Do Rio De Janeiro

“…A maioria dos estudos relata a detecção da forma larval em pacas, Cuniculus paca, e no ser humano, ambos hospedeiros intermediários natural e acidental do E. vogeli, respectivamente (D'ALESSANDRO et al, 1981;D'ALESSANDRO & RAUSCH, 2008;D'ALESSANDRO, 1997;NOYA-ALARCÓN et al, 2011;ALMEIDA et al, 2013;MAYOR et al, 2015;ALMEIDA et al, 2015;DEBOURGOGNE et al, 2017;BITTENCOURT-OLIVEIRA et al, 2018). Apesar da disponibilidade de anti-helmínticos eficientes para cães, essas doenças persistem em áreas endêmicas, sobretudo em países com ausência de programas de controle ou, quando presentes, ineficazes (DEPLAZES et al, 2011;NEVES et al, 2017).…”