First-line diuretics versus other classes of antihypertensive drugs for hypertension

Reinhart, Marcia; Puil, Lorri; Salzwedel, Douglas M; Wright, James M

doi:10.1002/14651858.cd008161.pub3

Cited by 3 publications

(1 citation statement)

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“…Anti-hypertension medication still serves as a major therapy choice for treating hypertension now. However, due to medication side effects, treatment resistance as well as economic factors, an extensive number of patients still have hypertension that cannot be successfully controlled ( 5 , 6 ). Therefore, it is essential to further explore a widely available, low-cost and sustainable treatment method ( 7 ).…”

Section: Introductionmentioning

confidence: 99%

Effects of different traditional Chinese exercise in the treatment of essential hypertension: a systematic review and network meta-analysis

Zhang,

Xu,

et al. 2024

Front. Cardiovasc. Med.

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BackgroundAs a therapy to prevent and treat essential hypertension (EH), traditional Chinese exercises (TCEs) were widely used in clinical practice. However, there is a lack of strictly comparison of the antihypertensive efficacy of different TCEs, which not conducive to the selection of the best and most optimal treatment. This study aimed to perform a network meta-analysis to objectively evaluate which TCE has the best effects in assisting with lowering blood pressure.MethodsPubMed, Embase, the Cochrane Library, Chinese National Knowledge Infrastructure (CNKI), VIP, SinoMed and Wanfang Data were searched for all randomized controlled trials (RCTs) on TCEs for the treatment of EH published up to July 10, 2023. RoB2.0 tool was utilized to evaluate the quality of the RCTs. The network meta-analysis was performed by R 4.1.2 and Stata 17.0. Weighted mean difference (WMD) was calculated for continuous outcomes.ResultsA total of 29 studies, including 2,268 patients were included to analyze 6 different interventions. The network meta-analysis results presented that in comparison with control group, Tai Chi + antihypertensive medication [WMD = −10.18, 95% CI, (−14.94, −5.44)] is the most effective intervention for lowering systolic blood pressure (SBP), and Wuqinxi + antihypertensive medication [WMD = −10.36, 95% CI (−18.98, −1.66)] is the most effective intervention for lowering diastolic blood pressure (DBP).ConclusionTCEs combined with antihypertensive medication may be able to achieve more prominent antihypertensive effects with Tai Chi and Wuqinxi potentially being the higher-priority options. However, well-designed randomized studies are warranted to further verify currently conclusion.

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Section: Introductionmentioning

confidence: 99%