First Example of Helices and Tubules in Aqueous Solution of a New Fluorescent Catanionic Sugar Surfactant

12-Hydroxystearic acid lipid tubes under various experimental conditions

“…There are a limited number of natural and synthetic lipids that can self-assemble into tubular structures, among which are glycolipids [7,8] and their bola-form derivatives [9] and phospholipids [6]. Most often, the tube-forming lipids are chiral molecules.…”

Giant vesicles of a single-tailed chiral cationic surfactant, (1R,2S)-(–)-N-dodecyl-N-methylephedrinium bromide, in water

“…Synthetic amphiphiles with different chemical structures and compositions of head groups and hydrocarbon tail(s) that can self-organize into vesicles in dilute aqueous solutions have been discussed in the recent literature [7][8][9][10][11][12][13]. Single-tailed cationic surfactants having azo linkages, unsaturation, or biphenyl moieties in the hydrocarbon chain have been found to form vesicles [14][15][16]. On the other hand, bola amphiphiles have been also reported to form bilayer vesicles [17][18][19][20].…”

Pharmaceutical applications for catanionic mixtures

“…For example, hollow polyhedrons have been found in catanionic mixtures of myrstic acid and CTAOH (Dubois et al 2001;Lootens et al 2003;Delorme et al 2006), as have catanionic discs (Zemb et al 1999). Other examples include Rosa et al (2006) who reported spontaneously formed cubosomes and hexosomes in catanionic mixtures of sodium hydrogenated tallow glutamate and arginine-N-lauroyl amide, and Blanzat et al (2001) who found helices and tubules in catanionic mixtures of 12-(4-amino-coumarin)-dodecanoic acid and N-octylaminolacticol.…”