First evidence of autochthonous cases of Leishmania (Leishmania) infantum in horse (Equus caballus) in the Americas and mixed infection of Leishmania infantum and Leishmania (Viannia) braziliensis

Soares, Isabel Roussoulieres; Silva, Soraia O.; Moreira, Filipe Moraghi; Prado, Luan Gavião; Fantini, Priscila; Maranhão, Renata de Pino Albuquerque; Filho, José Monteiro da Silva; Melo, Maria Norma; Palhares, Maristela Silveira

doi:10.1016/j.vetpar.2013.06.014

Cited by 54 publications

(53 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The results of this study are different to those suggested by Soares et al (2013), who performed the IFAT in 210 horses originating from the city of Belo Horizonte, Minas Gerais, and 65.20% (137/210) presented with anti-Leishmania spp. antibodies.…”

Section: Inoculated Four Equus Asinuscontrasting

confidence: 99%

Presence of anti-Leishmania spp. antibodies in slaughter horses in Brazil

Evers

Ferreira

Navarro

et al. 2017

SCA

View full text Add to dashboard Cite

The objective of this study was to investigate the presence of anti-Leishmania spp. antibodies using an indirect immunofluorescence technique in the serum of equidae slaughtered in two slaughterhouses registered with the Federal Inspection Service. Titers greater than 40 were considered reagents. Blood samples were collected from 398 animals of both sexes, with different ages, and coming from six Brazilian states, of which 46.0% (183/398) were reactive, indicating that these animals were exposed to the leishmaniasis agent that is widely distributed in Brazil. Key words: Slaughterhouse. Equine. Leishmaniosis. IFAT. Serology. ResumoO objetivo deste estudo foi investigar a presença de anticorpos anti-Leishmania spp. utilizando a técnica de imunofluorescência indireta em amostras de soro de equídeos abatidos em dois matadouros registrados no Serviço de Inspeção Federal. Os títulos superiores a 40 foram considerados reagentes. Foram coletadas amostras de sangue de 398 animais de ambos os sexos, com diferentes idades e provenientes de seis estados brasileiros, dos quais 46,0% (183/398) foram reativos, indicando que esses animais foram expostos ao agente de leishmaniose, amplamente distribuído no Brasil. Palavras-chave: Matadouro. Equinos. Leishmaniose. RIFI. Sorologia.

show abstract

Section: Inoculated Four Equus Asinuscontrasting

confidence: 99%

Presence of anti-Leishmania spp. antibodies in slaughter horses in Brazil

Evers

Ferreira

Navarro

et al. 2017

SCA

View full text Add to dashboard Cite

show abstract

“…Indeed, clinical cases of naturally acquired leishmaniasis have occasionally been found in horses in transmission areas in Brazil, specifically São Paulo [69] and Minas Gerais [70], and in Venezuela [71]. …”

Section: Discussionmentioning

confidence: 99%

Leishmania infection and blood food sources of phlebotomines in an area of Brazil endemic for visceral and tegumentary leishmaniasis

Guimarães-E-Silva

Silva

et al. 2017

PLoS ONE

Self Cite

View full text Add to dashboard Cite

The aims of the study were to determine the blood feeding preferences of sandflies and to identify species of Leishmania that infected phlebotomines in Caxias, Maranhão, Brazil, an area that is highly endemic for leishmaniasis. Sandflies were captured in light traps located in the peridomiciliary environments of randomly selected houses in urban and rural settings between 1800 and 0600 hours on new moon days between March 2013 and February 2015. DNA extracts from 982 engorged female sandflies were submitted to fragment length polymorphism analysis to identify infecting species of Leishmania, and blood sources were identified for 778 of these specimens. Infection by Leishmania infantum was detected in Lutzomyia longipalpis, Lu. whitmani and Lu. termitophila; L. infantum/L. braziliensis in Lu. longipalpis, Lu. whitmani and Lu. trinidadensis; L. shawi in Lu. longipalpis; L. mexicana in Lu. longipalpis; L. braziliensis in Lu. longipalpis and Lu. whitmani; L. guyanensis in Lu. longipalpis and Lu. termitophila; L. amazonensis in Lu. longipalpis and L. lainsoni or L. naiffi in Lu. longipalpis, while Lu. longipalpis and Lu. trinidadensis were infected with unidentified Leishmania sp. Blood sources were identified in 573 individual phlebotomines and the preferred hosts were, in decreasing order, chicken, dog, rodent and human with lower preferences for pig, horse, opossum and cattle. Lu. longipalpis and Lu. whitmani performed mixed feeding on man, dog and rodent, while Lu. longipalpis was the most opportunistic species, feeding on the blood of all hosts surveyed, but preferably on dog/chicken, dog/rodent and rodent/chicken. Our findings reveal the concomitant circulation of Leishmania species that cause visceral leishmaniasis and tegumentary leishmaniasis in the study area, and explain the occurrence of autochthonous human cases of both clinical forms of leishmaniasis in Caxias, Maranhão. The results support our hypothesis that, in the municipality of Caxias, transmission of Leishmania occurs in close proximity to humans.

show abstract

“…However, a large number of mammalian species have been reported as hosts of Leishmania (BRANDAO-FILHO et al, 2003) with reports occurring in domestic animals, increasing worldwide (SOARES et al, 2013) including in horses (BARBOSA-SANTOS et al, 1994).Clinical cases of cutaneous leishmaniosis in domestic animals such as dogs and horses are becoming relatively common in South (BARBOSA-SANTOS et al, 1994) and North America (RAMOS-VARA et al, 1996). However, despite the occurrence of these cases, the role of equids in the transmission of leishmaniosis has not been fully elucidated, even though these animals are considered as putative host of L. braziliensis in the Americas (TOLEZANO, 1994).…”

mentioning

confidence: 99%

Seroepidemiology ofLeishmaniaspp. in equids from Uberlândia, Minas Gerais, Brazil

et al. 2017

View full text Add to dashboard Cite

This study evaluated the occurrence of Leishmania spp. in equids from Uberlândia, Minas Gerais, Southeastern Brazil. Serum samples from 257 healthy equids of Uberlândia were assessed for the presence of antibodies against Leishmania spp. by using the indirect fluorescent-antibody test. Additionally, an epidemiological survey was done to evaluate the possible risk factors (species of equids, age, gender, economic activity, and contact with domestic and wild animals) associated with the presence of antibodies against Leishmania spp. The total seroprevalence against Leishmania spp. was 24.1% (62/257); representing seroprevalence levels of 22.7% (55/242) in horses, 50% (4/8) in mules, and 42.9% (3/7) in ponies from all regions evaluated. The species of equid was the only factor that contributed to an elevated seroprevalence of Leishmania spp.

show abstract

First evidence of autochthonous cases of Leishmania (Leishmania) infantum in horse (Equus caballus) in the Americas and mixed infection of Leishmania infantum and Leishmania (Viannia) braziliensis

Cited by 54 publications

References 31 publications

Presence of anti-Leishmania spp. antibodies in slaughter horses in Brazil

Presence of anti-Leishmania spp. antibodies in slaughter horses in Brazil

Leishmania infection and blood food sources of phlebotomines in an area of Brazil endemic for visceral and tegumentary leishmaniasis

Seroepidemiology ofLeishmaniaspp. in equids from Uberlândia, Minas Gerais, Brazil

Contact Info

Product

Resources

About