First case of Pasteurella multocida endocarditis of the tricuspid valve: a favorable outcome following medical treatment

Naba, Mazen R.; Araj, George F.; Kanafani, Zeina A.; Kanj, Souha S.

doi:10.1016/j.ijid.2008.11.004

Cited by 15 publications

(14 citation statements)

References 13 publications

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“…Leukocyte and neutrophil counts are typically high at the infection site, and inflammation develops very rapidly. In more severe cases, pasteurellosis can rapidly progress to bacteremia (fulminant sepsis) (41, 161,235,241,251,[256][257][258][259][260][261][262][263][264][265][266] and other complications such as osteomyelitis (inflammation of the bone) (155,165,(267)(268)(269), endocarditis (inflammation of the heart) (256,263,(270)(271)(272)(273)(274)(275)(276)(277)(278)(279)(280)(281)(282)(283)(284)(285), and meningitis (inflammation of the meninges) (53, 90, 159, 163, 165, 264, 286-293).…”

Section: Pasteurella and Other Pasteurellaceae Diseases In Humans Pasmentioning

confidence: 99%

Pasteurella multocida: from Zoonosis to Cellular Microbiology

2013

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SUMMARY In a world where most emerging and reemerging infectious diseases are zoonotic in nature and our contacts with both domestic and wild animals abound, there is growing awareness of the potential for human acquisition of animal diseases. Like other Pasteurellaceae , Pasteurella species are highly prevalent among animal populations, where they are often found as part of the normal microbiota of the oral, nasopharyngeal, and upper respiratory tracts. Many Pasteurella species are opportunistic pathogens that can cause endemic disease and are associated increasingly with epizootic outbreaks. Zoonotic transmission to humans usually occurs through animal bites or contact with nasal secretions, with P. multocida being the most prevalent isolate observed in human infections. Here we review recent comparative genomics and molecular pathogenesis studies that have advanced our understanding of the multiple virulence mechanisms employed by Pasteurella species to establish acute and chronic infections. We also summarize efforts being explored to enhance our ability to rapidly and accurately identify and distinguish among clinical isolates and to control pasteurellosis by improved development of new vaccines and treatment regimens.

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Section: Pasteurella and Other Pasteurellaceae Diseases In Humans Pasmentioning

confidence: 99%

Pasteurella multocida: from Zoonosis to Cellular Microbiology

2013

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“…1 Ten out of twenty-one (47.6%) endocarditis cases described in the literature had close contact with animals detailed in the clinical history. 2–10 Our patient did not have a clear history of bites or scratches but he did have two cats at home and close contact with dogs at his sister's house. He was also receiving immunosuppressive therapy after his renal transplant.…”

Section: Discussionmentioning

confidence: 89%

“…To our knowledge this is the twenty-first reported case of endocarditis but the first to be reported in a penicillin allergic patient. 2–10 As with previous cases, the diagnosis of infective endocarditis was made according to Duke criteria: one major criterion (evidence of endocardial involvement) and three minor criteria (predisposing heart condition, fever and microbiological evidence with positive blood culture). Laboratory isolation and identification of P. multocida was performed using standard microbiological techniques: API-20NE, API-20E (BioMerieux) and the Phoenix Automated System (BD).…”

Section: Discussionmentioning

confidence: 99%

Prosthetic Valve Endocarditis Caused by Pasteurella in a Penicillin Allergic Patient: Challenges in Diagnosis and Treatment

Satta

Gorton

Kandil

2012

Infectious Disease Reports

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Pasteurella multocida is a rare cause of infective endocarditis with only a few cases described. This report involves a 38-year-old penicillin-allergic patient in an immunocompromised state with several co-morbidities. Two molecular microbiological techniques, 16S rRNA sequencing and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry were used to confirm the species identification as P. multocida. Previous reports in the literature are also reviewed.

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“…Like other forms of endocarditis, P. multocida IE is also associated with clinical manifestations including arterial emboli (18,22) and mycotic aneurysms (22). The infection appears to show no preference for the valves involved on the left side of the heart, with the aortic and mitral valves being affected nearly equally (13), and with the tricuspid and pulmonic valves having been affected in a patient after a cat bite (23) and in an intravenous drug user (24), respectively.…”

Section: Discussionmentioning

confidence: 96%

<i>Pasteurella multocida</i> Infective Endocarditis: A Possible Link with Primary Upper Respiratory Tract Infection

et al. 2015

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A 50-year-old Japanese man presented with fever and upper respiratory tract symptoms that required urgent inpatient admission. A physical examination revealed conjunctival hemorrhages and peripheral embolic phenomena. Blood cultures grew Pasteurella multocida, and an echocardiography revealed a mitral valve vegetation suggestive of infective endocarditis (IE), which was confirmed using the Modified Duke Criteria. After several antibiotic regimens proved ineffective, valve replacement was performed, with a good eventual outcome. P. multocida IE is rare and may sometimes have no preceding risk factors. P. multocida infections of the upper respiratory tract are unusual but may be an inciting event for IE. It is essential to check blood cultures and to repeat the performance of physical examinations to appreciate the developing features of IE.

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First case of Pasteurella multocida endocarditis of the tricuspid valve: a favorable outcome following medical treatment

Cited by 15 publications

References 13 publications

Pasteurella multocida: from Zoonosis to Cellular Microbiology

Pasteurella multocida: from Zoonosis to Cellular Microbiology

Prosthetic Valve Endocarditis Caused by Pasteurella in a Penicillin Allergic Patient: Challenges in Diagnosis and Treatment

<i>Pasteurella multocida</i> Infective Endocarditis: A Possible Link with Primary Upper Respiratory Tract Infection

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