First-borns have greater BMI and are more likely to be overweight or obese: a study of sibling pairs among 26 812 Swedish women

Derraik, José G. B.; Ahlsson, Fredrik; Lundgren, Maria; Jonsson, Björn; Cutfield, Wayne S.

doi:10.1136/jech-2014-205368

Cited by 24 publications

(20 citation statements)

References 21 publications

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“…In addition, the Register does not record paternal anthropometric data, so that the possible associations between fathers’ and daughters’ BMI could not be investigated. Further, as this study only covered first-born daughters, future studies should assess whether a similar trend exist among later-born daughters, especially since we have recently shown that first-borns have greater BMI and increased odds of obesity compared to their second-born sisters in Sweden 22 . Lastly, there were very limited data on maternal birth parameters, so that we were unable to exclude mothers born preterm, from multiple births, or congenital malformations.…”

Section: Discussionmentioning

confidence: 98%

Obesity rates in two generations of Swedish women entering pregnancy and associated obesity risk among adult daughters

Derraik

Ahlsson

Diderholm

et al. 2015

Sci Rep

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We examined changes in obesity rates in two generations of Swedish women entering pregnancy, and assessed the effects of maternal body mass index (BMI) on the risk of overweight or obesity among adult daughters. This study covered an intergenerational retrospective cohort of 26,561 Swedish mothers and their 26,561 first-born daughters. There was a 4-fold increase in obesity rates, which rose from 3.1% among women entering pregnancy in 1982–1988 to 12.3% among their daughters in 2000–2008 (p < 0.0001) when entering pregnancy. The greater the maternal BMI, the greater the odds of overweight and/or obesity among daughters. Underweight mothers had half the odds of having an overweight or obese daughter in comparison to mothers of normal BMI (p < 0.0001). In contrast, the odds ratio of obese mothers having obese daughters was 3.94 (p < 0.0001). This study showed a strong association between maternal obesity and the risk of obesity among their first-born daughters. In addition, we observed a considerable increase in obesity rates across generations in mother-daughter pairs of Swedish women entering pregnancy. Thus, it is important to have preventative strategies in place to halt the worsening intergenerational cycle of obesity.

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Section: Discussionmentioning

confidence: 98%

Obesity rates in two generations of Swedish women entering pregnancy and associated obesity risk among adult daughters

Derraik

Ahlsson

Diderholm

et al. 2015

Sci Rep

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“…Anthropometric differences in adulthood were examined with generalized linear regression models. All adjusted models included the smoking habit of the woman's mother during pregnancy 31 , birth order 32,33 , and year of birth (to account for population-wide trends). Weight and BMI models also included current regular smoking (pre-pregnancy and/or during pregnancy) and age, while the "weight [ht adj]" model also adjusted for current height.…”

Section: Study Populationmentioning

confidence: 99%

Large-for-gestational-age phenotypes and obesity risk in adulthood: a study of 195,936 women

Derraik

Maessen

Gibbins

et al. 2020

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While there is evidence that being born large-for-gestational-age (LGA) is associated with an increased risk of obesity later in life, the data are conflicting. Thus, we aimed to examine the associations between proportionality at birth and later obesity risk in adulthood. This was a retrospective study using data recorded in the Swedish Birth Register. Anthropometry in adulthood was assessed in 195,936 pregnant women at 10-12 weeks of gestation. All women were born at term (37-41 weeks of gestation).LGA was defined as birth weight and/or length ≥2.0 SDS. Women were separated into four groups: appropriatefor-gestational-age according to both weight and length (AGA -reference group; n = 183,662), LGA by weight only (n = 4,026), LGA by length only (n = 5,465), and LGA by both weight and length (n = 2,783). Women born LGA based on length, weight, or both had BMI 0.12, 1.16, and 1.08 kg/m 2 greater than women born AGA, respectively. The adjusted relative risk (aRR) of obesity was 1.50 times higher for those born LGA by weight and 1.51 times for LGA by both weight and height. Length at birth was not associated with obesity risk. Similarly, women born LGA by ponderal index had BMI 1.0 kg/m 2 greater and an aRR of obesity 1.39 times higher than those born AGA. Swedish women born LGA by weight or ponderal index had an increased risk of obesity in adulthood, irrespective of their birth length. Thus, increased risk of adult obesity seems to be identifiable from birth weight and ignoring proportionality.

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“…However, birth order may also be of importance as lower birth order has been linked to higher BMI (19) , fat mass (12) , and overweight or obesity (20) .…”

mentioning

confidence: 99%

Maternal pre-pregnancy BMI and offspring body composition in young adulthood: the modifying role of offspring sex and birth order

Chaparro¹,

Koupil²,

Byberg³

2017

Public Health Nutr.

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First-borns have greater BMI and are more likely to be overweight or obese: a study of sibling pairs among 26 812 Swedish women

Abstract: Our study corroborates other large studies on men, and the steady reduction in family size may contribute to the observed increase in adult BMI worldwide.

Cited by 24 publications

References 21 publications

Obesity rates in two generations of Swedish women entering pregnancy and associated obesity risk among adult daughters

Obesity rates in two generations of Swedish women entering pregnancy and associated obesity risk among adult daughters

Large-for-gestational-age phenotypes and obesity risk in adulthood: a study of 195,936 women

Maternal pre-pregnancy BMI and offspring body composition in young adulthood: the modifying role of offspring sex and birth order

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