Finite element analysis of brain contusion: An indirect impact study

Huang, Haw Ming; Lee, M. C.; Lee, S. Y.; Chiu, Wen Ta; Pan, Li-Chern; Chen, C. T.

doi:10.1007/bf02347044

Cited by 39 publications

(21 citation statements)

References 34 publications

(46 reference statements)

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“…Huang et al [9] suggested that SS was more likely to be a better criterion than ICP when predicting brain contusion if the head was subjected to indirect impact. Chu et al [35] reported that plane shear stress predicted by a 2D head model accounted for contusion injury.…”

Section: Discussionmentioning

confidence: 98%

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Investigation of brain contusion mechanism and threshold by combining finite element analysis with in vivo histology data

Mao

Yang

2011

Numer Methods Biomed Eng

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SUMMARYA previously validated, highly detailed three-dimensional finite element (FE) rat brain model was used to correlate FE model-predicted intracranial responses with experimentally measured brain contusions. In the published in vivo experimental study, the animals were injured via a controlled cortical impact device at two different severities and the location and volume of contusion measured at 24 h post injury. Brain internal responses, including the maximum principal strain (MPS), maximum shear strain (MSS), shear strain (SS) in the coronal plane, strain energy density (SED), and intracranial pressure (ICP), were investigated through FE simulations. Distributions of MPS, MSS, and SED were comparable with the shapes of contusion observed experimentally. However, the regions with high positive ICP were not found to correlate with the regions of brain contusion. Locations of high SS were in the vicinity of the experimental contusion region, but the shallow shape of the SS distribution differed greatly from contusion observed experimentally. This study suggests that MPS, MSS, and SED are candidate injury mechanisms for brain contusion, and the corresponding threshold for predicting the contusion volume measured at 24 h post injury is 0.265 MPS, 0.281 MSS, or 1.72E−5 (J/mm 3 ) SED based on the current FE model.

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Section: Discussionmentioning

confidence: 98%

“…There have been arguments regarding whether intracranial pressure (ICP) or tissue strain causes brain contusions [9,10]. Traditionally, positive (compressive) ICP has been believed to induce brain contusion under the impact site [11].…”

Section: Introductionmentioning

confidence: 99%

Investigation of brain contusion mechanism and threshold by combining finite element analysis with in vivo histology data

Mao

Yang

2011

Numer Methods Biomed Eng

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“…Real human material coefficients of Young's modulus, Poisson's ratio and density 1,2,3,7 are selected for analysis and shown in Table 1. The boundary conditions for both simple and complex models are set completely fixed in X, Y, Z directions at the cross section of the junction of the brain and brain stem, respectively.…”

Section: Finite Element Analysismentioning

confidence: 99%

“…Analysis results illustrated that shear strain theory seemed better able to explain mechanism of brain contusion caused by the impact of brain or hindbrain. Huang et al 3 used 3-dimensional (3D) finite element analysis to study the cerebral contusion. The model was first validated against a set of experimental results from the literature.…”

Section: Introductionmentioning

confidence: 99%

Dynamic analysis of the human brain with complex cerebral sulci

Tseng

Huang

et al. 2016

Bioengineered

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(2016) Dynamic analysis of the human brain with complex cerebral sulci, Bioengineered, 7:4, 219-225, DOI: 10.1080/21655979.2016 ABSTRACTThe brain is one of the most vulnerable organs inside the human body. Head accidents often appear in daily life and are easy to cause different level of brain damage inside the skull. Once the brain suffered intense locomotive impact, external injuries, falls, or other accidents, it will result in different degrees of concussion. This study employs finite element analysis to compare the dynamic characteristics between the geometric models of an assumed simple brain tissue and a brain tissue with complex cerebral sulci. It is aimed to understand the free vibration of the internal brain tissue and then to protect the brain from injury caused by external influences. Reverse engineering method is used for a Classic 5-Part Brain (C18) model produced by 3B Scientific Corporation. 3D optical scanner is employed to scan the human brain structure model with complex cerebral sulci and imported into 3D graphics software to construct a solid brain model to simulate the real complex brain tissue. Obtaining the normal mode analysis by inputting the material properties of the true human brain into finite element analysis software, and then to compare the simplified and the complex of brain models.

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“…Although the numerical analysis by finite element method has accomplished large development and become powerful tool for researchers recently [4][5][6][7], it is still important to verify the analytical result by the experiment using the simple physical model which has an analogy on a fundamental structure with a human head [8].…”

Section: Introductionmentioning

confidence: 99%

Numerical and experimental study on cerebral contusion under impact loading

Aomura¹,

Fujiwara²,

Nishimura³

2005

Modelling in Medicine and Biology VI

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The mechanism of brain contusion is investigated using a finite element analysis. Prior to the numerical calculation for a finite element human head model, the experimental study of an impact loading for a water-filled acrylic cylindrical container was carried out in order to observe the fundamental physical phenomenon and to confirm the validity of the finite element analysis in comparison with the both numerical and experimental results. After the stroke, the deflection of the acrylic container wall propagated in both sides of the stroke point, and large negative pressure was generated just in the opposite side of the stroke point when deflections from both sides met. The time taken until the deflection reached the opposite side was close to the natural period of the waterfilled container and the period of fluctuation of internal pressure was equal to the natural frequency of the water-filled container. In numerical analysis the amplitude of the pressure fluctuation was slightly bigger for the tied container wall-water interface condition than for slide condition, and the damping was slightly bigger for the slide condition than for the tied condition, although the numerical and experimental pressure responses resembled each other approximately. Next, the human head model was analysed by FEM and the result was compared with the result of the experimental study reported by Nahum and good agreement was obtained. Five more loading cases were investigated. The deflection of the skull gave a large effect on the fluctuation of the internal pressure also for both coup and conrecoup contusions. Although in the frontal, occipital and under occipital region strokes the intracranial pressure of the coup and the contrecoup side was almost the same, in the parietal and temporal region strokes the intracranial pressure in the coup side was bigger than the contrecoup side.

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Finite element analysis of brain contusion: An indirect impact study

Cited by 39 publications

References 34 publications

Investigation of brain contusion mechanism and threshold by combining finite element analysis with in vivo histology data

Investigation of brain contusion mechanism and threshold by combining finite element analysis with in vivo histology data

Dynamic analysis of the human brain with complex cerebral sulci

Numerical and experimental study on cerebral contusion under impact loading

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