Fingerprint–efficacy study of artificial Calculus bovis in quality control of Chinese materia medica

Quality Control Method for Herbal Medicine - Chemical Fingerprint Analysis

“…In recent years, the fingerprint-efficacy study caused the scientists' interests, and many studies have been down or ongoing. For instance, for quality control of artificial Calculus bovis, an attempt on fingerprint-efficacy study of artificial C. bovis was developed in the literature (Kong W.J, et al, 2011). In this study, the chemical fingerprints of 10 batches of artificial C.bovis sample from various sources were established by UPLC-ELSD.…”

A High Performance Liquid Chromatography and Electrospray Ionization Mass Spectrometry Method for the Analysis of the Natural Medicine,Forsythia Suspensa

“…The HCA method attempts to assign a degree of class membership to an object over a number of classes (Peng et al 2011). The Ward's method and the Euclidean distance were used to establish the clusters (Kong et al 2011).…”

“…Vahl (''lianqiao'' in Chinese) is widely distributed in China, Korea, Japan, and some European countries (Jiao et al 2012), and its fruit contains biologically active compounds, which display strong anti-bacterial, antiviral, anti-oxidant, and anti-inflammatory properties as well as inhibitory effects, attributed to the presence of cyclic adenosine monophosphate phosphodiesterase (cAMP) (Dai et al 2009;Xia et al 2011;Xue et al 2010). According to the Chinese Pharmacopoeia (Chinese Pharmacopoeia Committee, 2010), this TCM has been used in China for many years, and it provides two types of fruit-raw and ripe, referred to in China as ''Qingqiao'' and ''Laoqiao,'' respectively. In general, chromatographic fingerprint techniques have played an important role in the quality control of the TCMs (Kong et al 2011); such methods have been employed for systemic characterization of the composition of different TCMs, in particular, focusing on the identification and assessment of stability of the medicinal components. Both the FDA (Food and Drug Administration 2000) and EMEA (European Medicines Agency 2006) have recommended that chromatographic fingerprints should be used to assess the quality of herbal medicines (B. G. Xie et al 2008).…”

Quantitative analysis of multi-components by single marker—a rational method for the internal quality of Chinese herbal medicine

“…Nowadays, Chinese herbal medicine (CHM) has been attracting attention increasingly due to its long-standing clinical application and reliable therapeutic efficacy 1, 2. Despite the great advances in modern pharmaceutical research, CHM continues to play an important role in the prevention and treatment of various diseases 3 .…”