Fine structure of Cysticercus celluosae from human brain

Abstract

A transmission electron microscopic study was conducted in order to know basic tegumental structure of Cysticercus cellulosae which was obtained from the ventricles of human brain. In general, the electron microscopic appearance of the tegument resembled that of the body wall of adult and larval forms of other cestodes. The tegument both of the parenchymatous portion (scolex and spiral canal) and bladder portion consisted of such components, i.e., an outer vesicular layer with microtriches, and an inner fibrous layer. The subtegumental tissue below the fibrous layer was filled with muscle bundles and tegumental cells. The surface of the larva was covered by the microtriches of two distictly different types. The characteristic pyramid-shaped "tetrahedral" form was observed on the surface of the scolex portion, whereas the elongated, slender "filamentous" microtriches were distributed on the regions of the spiral canal and bladder portion. The tegumental and subtegumental tissues varied in thickenss from one region to the next. The possibility of application in making differential diagnosis from other larval cestodes and possible fuction of this larval tegument were discussed.

Subcutaneous cysticercosis diagnosed by mitochondrial DNA analysis

“…Development of immature tapeworms in human tissues results in various syndromes depending on the particular species of parasites, including cysticercosis and sparganosis. In some cases, after careful examination of subserial sections, diagnostic scolex of Cysticerus cellulosae can sometimes be seen 1,6 . Another morphological structure of diagnostic value in cysticerci is an external tissue or “bladder wall” which is relatively narrow, in direct contact with host tissue, and in most areas separated from the inner portion 9 .…”

“…Cysticercus cellulosae, the larval stage of Taenia solium, is usually more pathogenic to humans than the adult tapeworm. 1 Cysticercosis prevails in the developing countries such as India, China, Mexico and Latin American countries where the majority of citizens belong to low socioeconomic status. [2][3][4] Clinical manifestations vary depending on the site of larval lodging, larval burden, and host reaction.…”

Characterization of S3Pvac Anti-Cysticercosis Vaccine Components: Implications for the Development of an Anti-Cestodiasis Vaccine

“…Moreover, it is also probable that both peptides could be detected in other organisms of medical relevance that belong to this monophyletic cestode taxon i.e. Hymenolepis, Dyphillobotrium, Spirometra [41], [42]. In addition, KETc1 in T. crassiceps ORF is detected in the outer surface of the tegument of the larval stage, indicating its presence in the microtriches of the tegument.…”

“…It also participates in defending the worm against the host's digestive enzymes. Furthermore, considering that the tegument's function and morphology is conserved in cestodes, it seems conceivable that KETc1 and GK1 expression across species is quite uniform [40], [41]. Moreover, it is also probable that both peptides could be detected in other organisms of medical relevance that belong to this monophyletic cestode taxon i.e.…”

“…In addition, KETc1 in T. crassiceps ORF is detected in the outer surface of the tegument of the larval stage, indicating its presence in the microtriches of the tegument. These are ciliated sensory structures that increase the absorptive area of the tapeworm [40], [41], [43].…”