Fine‐needle aspiration cytology of orbital and eyelid lesions

Abstract

Fine-needle aspiration cytology (FNAC) of orbital lesions is now increasingly popular. Because of its unique location and the occurrence of varieties of lesions, diagnosis of orbital lesion is a challenge to the cytopathologists. FNAC of orbital and eyelid tumors is a suitable diagnostic technique that necessitates close co-operation between the ophthalmologist and pathologist. No radical procedure should be planned on the basis of FNAC, but it allows the diagnosis of a new primary lesion or the recurrence or metastasis of a tumor and can be done to identify lesions that require either specific medical therapy, as in nonresectable, inflammatory, and lymphoid tumors, or limited surgery for benign resectable neoplasms. With the help of various ancillary techniques a definitive diagnosis is possible on orbital and adnexal lesions. It is essential to have a detailed knowledge on the FNAC of these lesions and their potential pitfalls. In this present review, we have discussed various orbital lesions, their clinical presentations, cytomorphology, and ancillary techniques to confirm the diagnosis.

Automated tru-cut imaging-guided core needle biopsy of canine orbital neoplasia. A prospective feasibility study

“…While these methods provide sufficient histological tissue, they require high morbidity surgical intervention (Slatter and Abdelbaki, 1979;Gilger et al, 1994;Boston, 2010;Hakannsson and Hakannsson, 2010;Gelatt and Withley, 2011;Spiess and Pot, 2013). In contrast, fine needle aspiration biopsy is effective and sometimes may be acceptable in ocular oncology (Tani et al, 2006;Agrawi et al, 2013;Nair and Sankar, 2014). Imaging-guided core needle A.…”

Fine needle aspiration cytology of orbital and ocular adnexal lesions

“…[2] This technique when performed in experienced hands is safe and of great value in the diagnosis of new primary, recurrent, and metastatic orbital tumors. [234] Moreover, it provides the considerable advantages to both patient and orbital surgeon in terms of shortening the hospitalization period, reduction of health care costs, and proper management of orbital lesions. [3] The reported diagnostic accuracy of this technique for orbital and adnexal lesions ranged from 47% to 100% and its diagnostic value has been increased with the help of various ancillary methods.…”

“…[3] The reported diagnostic accuracy of this technique for orbital and adnexal lesions ranged from 47% to 100% and its diagnostic value has been increased with the help of various ancillary methods. [235678910] In a series by Nag et al,[11] the sensitivity and specificity of FNAC in the diagnosis of orbital lesions was 86.6% and 100%, respectively. Although no major surgical intervention should be planned only based on FNAC results, this technique can be beneficial for planning further medical or limited surgical management of the orbital and adnexal lesions.…”

The Role of Fine Needle Aspiration of Orbital Lesions: A Case Series

“…Pleomorphic adenomas account for up to 8 of 29 cases of benign orbital tumors in recent studies [2]. Fortunately, these types of tumors have extremely typical cytological features and can be diagnosed with such a low-impact technique, for they tend to spread locally rather easily, with serious consequences on the prognostic outlook.…”

“…Moreover, the periocular area is a particularly delicate region, thus invasive diagnostic techniques are to be used sparingly in order to keep the risk of complications as low as possible. In the majority of cases, a tissue sample is often required and fine-needle aspiration (FNA) biopsy has been extensively used and studied since the 1970s [2]. Preoperative clinical and radiological findings, although essential, are not completely capable of providing a conclusive diagnosis for etiological definition and therapeutic purposes.…”