Fine needle aspiration cytology of orbital and ocular adnexal lesions

Cytomorphology of sebaceous carcinoma of the eyelid: A short series of three cases with literature review

“…While necrosis, papillaroid fragments, and crushing artifacts were also evident to clinch the diagnosis (Table 2). Kanavi et al found a concordance rate of 90% between the FNAC and histopathology results in various orbital and eyelid lesions, while in our study, it was 100% 13 . Special stain (Sudan IV and Oil Red O) and immunostain using a panel of antibodies such as BerEP4, adipophilin (ADP), epithelial membrane antigen (EMA), and androgen receptor (AR) help to confirm the diagnosis of SC and differentiate from SCC, BCC, and malignant melanoma 3 .…”

“…Kanavi et al found a concordance rate of 90% between the FNAC and histopathology results in various orbital and eyelid lesions, while in our study, it was 100%. 13 Special stain (Sudan IV and Oil Red O) and immunostain using a panel of antibodies such as BerEP4, adipophilin (ADP), epithelial membrane antigen (EMA), and androgen receptor (AR) help to confirm the diagnosis of SC and differentiate from SCC, BCC, and malignant melanoma. 3 The recommended treatment modality of OSC is wide local excision (5-6-mm surgical margin) or Mohs' micrographic surgery (2-mm margin) followed by eyelid reconstruction.…”

A comprehensive review of biopsy techniques for oculoplastic and orbital surgeons from ophthalmic pathologists’ perspective

“…[ 9 ] It was not recommended generally for diagnosing benign encapsulated orbital tumors and its yield was thought to be limited in the diagnosis of lymphoid tumors. [ 9 10 ] FNAB requires special arrangements between the orbital surgeon who needs to have adequate experience with the FNAB technique and the cytopathologist who has particular expertise in orbital pathology. Katavi has nicely summarized the application of FNAB in the diagnosis of orbital and adnexal tumors and concluded the importance of patient selection, experience, availability of ancillary testing, and imaging guidance.…”

“…Katavi has nicely summarized the application of FNAB in the diagnosis of orbital and adnexal tumors and concluded the importance of patient selection, experience, availability of ancillary testing, and imaging guidance. [ 10 ] In addition, several drawbacks to this technique application in the orbit in comparison to its use for intraocular tumors because of the complexity of orbital structures and difficulties that might be faced in reaching deep-seated retrobulbar lesions without causing damage to vital structures such as the globe or the optic nerve. [ 10 11 ] Gupta et al .…”

“…[ 10 ] In addition, several drawbacks to this technique application in the orbit in comparison to its use for intraocular tumors because of the complexity of orbital structures and difficulties that might be faced in reaching deep-seated retrobulbar lesions without causing damage to vital structures such as the globe or the optic nerve. [ 10 11 ] Gupta et al . in a study that has included 37 patients with orbital mass lesions, out of which 19 were located in the posterior aspect of the orbit-described the technique for ultrasound-guided freehand FNAB using a 25-gauge needle.…”