Fine Needle Aspiration Cytology of Cutaneous Vascular Tumours

Pérez‐Guillermo, Miguel; Pérez, J.; Rojo, Blas; Gil, Ari

doi:10.1111/j.1365-2303.1992.tb00513.x

Cited by 25 publications

(18 citation statements)

References 7 publications

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“…The scattered spindled endothelial cells gave the impression of stromal cells and the clusters of round cells that had imbibed fibrin gave a false impression of multinucleate giant cells of GCT. The fact that endothelial cells in IPEH can imbibe fibrin has also been highlighted in another study [5]. The cytologic features of these 2 cases have been compared with other published cases (table 1).…”

Section: Discussionmentioning

confidence: 95%

“…The published cytologic literature describes a varied morphology leading to frequent misdiagnoses [3,4,5,6,7,8]. The case reported by García-Macías et al [4] was cytologically diagnosed as vascular mesenchymal tumor of suspected malignancy because of the polymorphic (two type) population of cells, prominent nucleoli, and occasional mitotic figures.…”

Section: Discussionmentioning

confidence: 99%

“…Rarely globules of eosinophilic material can also be seen in angiosarcoma. In hemangioma, smears show sparse cellularity in a background of red blood cells [5,10]. The cells are present in loose syncytial groups and have ovoid and/or carrot-shaped nuclei with finely pointed ends.…”

Section: Discussionmentioning

confidence: 99%

“…Knowledge of the cytopathologic features of IPEH is also important as it can be misdiagnosed as other vascular lesions like angiosarcoma, hemangioma, and glomus tumor [5,10]. In angiosarcoma, aspirate is usually abundant and architectural patterns like pseudoacini, branching pseudopapillary structures, and rosettes can be seen [11].…”

Section: Discussionmentioning

confidence: 99%

“…It presents clinically as a small, firm, superficial mass most commonly in veins of the head and neck or limbs. Fine-needle aspiration (FNA) findings of this lesion have been described as isolated case reports in the literature [3,4,5,6,7,8]. In the majority of cases a definite diagnosis of IPEH could not be made cytologically.…”

Section: Novel Insightsmentioning

confidence: 99%

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Cytologic Diagnosis of Intravascular Papillary Endothelial Hyperplasia: A Report of Two Cases and Review of Cytologic Literature

Handa¹,

Khurana²,

Singhal³

et al. 2012

Acta Cytologica

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Background: Intravascular papillary endothelial hyperplasia (IPEH), previously known as ‘Masson’s hemangioma’, is a reactive endothelial proliferation that occurs most commonly in the vessels of the head, neck, and extremities. The cytologic findings of the lesion are varied and depend on the age of the lesion. Cases: Case 1 is a 61-year-old man who presented with a swelling on the medial aspect of the forearm. The clinical diagnosis was lipoma. Cytologic smears showed spindle cells tagging onto a rich capillary network and smaller round cells arranged around hyaline cores. The cytologic diagnosis was benign vascular tumor. On histolopathogic examination a diagnosis of IPEH was given. Case 2 is a 45-year-old man who presented with swelling on the dorsal aspect of the wrist. The cytologic diagnosis of giant cell tumor was made based on the presence of scattered spindled cells and multinucleate giant cells. The giant cells had various shapes like round or crescent and had 10–25 nuclei. The lesion was excised and a diagnosis of IPEH was rendered. Conclusion: These two cases highlight the varied cytomorphology of IPEH making the pinpoint diagnosis of this lesion difficult on cytologic smears.

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Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Novel Insightsmentioning

confidence: 99%

See 3 more Smart Citations

Cytologic Diagnosis of Intravascular Papillary Endothelial Hyperplasia: A Report of Two Cases and Review of Cytologic Literature

Handa¹,

Khurana²,

Singhal³

et al. 2012

Acta Cytologica

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Hepatic angiosarcoma: Aspiration biopsy cytology and immunocytochemical contribution

Saleh

Tao

1998

Diagn. Cytopathol.

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In the absence of previously documented sarcoma, the initial diagnosis of angiosarcoma (AS) on fine‐needle aspiration (FNA) biopsy of the liver is difficult. However, awareness of its occurrence and the assistance of immunocytochemical stains may aid in arriving at the correct diagnosis. In this paper, a 59‐yr‐old smoker and alcoholic woman presented after a syncopal episode and was found to have a palpable right abdominal mass. An abdominal CT scan confirmed multiple centrally necrotic liver masses, from which an FNA biopsy was obtained. The smears were bloody with groups of relatively dishesive and singly dispersed spindle cells in a somewhat necrotic background. The nuclei were elongated to ovoid‐round with small nucleoli. The cytoplasm was ample and ill‐defined. The cells were reactive for factor VIII‐related antigen and CD31 but negative for cytokeratin immunocytochemical stains, and a diagnosis of “suspicious for angiosarcoma” was entertained. The patient declined further studies or treatment but presented 4 mo later with light‐headedness and hypoglycemia. Laparoscopic tissue biopsies of the liver/abdominal masses were obtained and revealed AS. Rarely, liver masses may represent AS. Pathologists should be aware of their cytomorphology and characteristic immunostaining to avoid their misinterpretation. Diagn. Cytopathol. 1998;18:208–211. © 1998 Wiley‐Liss, Inc.

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Basal-cell carcinoma: Cytologic and immunocytochemical findings in fine-needle aspirates

et al. 1998

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The smears of fine‐needle aspirates corresponding to 137 histologically proven basal‐cell carcinomas (BCCs) were reviewed. Satisfactory for evaluation were 127 smears; the remaining 10 were unsatisfactory. In 124 cases (97.6%), the cytologic diagnoses coincided with the histologic ones. The remaining 3 were false negatives, and the subsequent histologic correlation demonstrated superficial BCC missed by the needle. The cytologic criteria that permitted a diagnosis of BCC were: variable‐sized and irregular‐shaped cohesive epithelial clusters, round to oval monomorphic nuclei, bland chromatin pattern, and sparse cytoplasm. In 35 cases, a panel of antibodies was used in the smears and in the respective histologic sections. Epithelial clusters of BCC showed an intense and diffuse positivity for AE‐3 and BerEP4, while UEAI and AE‐1 were negative. Although HMB45 and S100‐A tested negative in the epithelial clusters, a faint and sparse focal positivity for HMB45 and S‐100A was seen in some clusters. This positivity is believed to correspond to just a few normal melanocytes and Langerhans cells trapped in the neoplastic epithelial clusters. In the histologic correlates, the same results were obtained, although HMB45 positivity was more conspicuous at the periphery of the neoplastic nests. Diagn. Cytopathol. 1998;18:403–408. © 1998 Wiley‐Liss, Inc.

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Fine Needle Aspiration Cytology of Cutaneous Vascular Tumours

Cited by 25 publications

References 7 publications

Cytologic Diagnosis of Intravascular Papillary Endothelial Hyperplasia: A Report of Two Cases and Review of Cytologic Literature

Cytologic Diagnosis of Intravascular Papillary Endothelial Hyperplasia: A Report of Two Cases and Review of Cytologic Literature

Hepatic angiosarcoma: Aspiration biopsy cytology and immunocytochemical contribution

Basal-cell carcinoma: Cytologic and immunocytochemical findings in fine-needle aspirates

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