Fine needle aspiration cytology of thyroid nodules at Kenyatta National Hospital, Nairobi

Abstract

Objective: To determine the pattern of thyroidal nodules diagnosed by (FNA) cytology. Design: A cross-sectional study. Setting: Kenyatta National Hospital (KNH)-a University of Nairobi affiliated hospital. Subjects: Forty two patients seen at FNA clinic at KNH between June and August 2001. Results: The female to male ratio was 7:1, with the majority in the age group 31-50 years. Overall 88.1% patients had benign FNA cytologic diagnostic results, 2.4% had a malignant, and a suspicious result respectively and 7.1% were non-diagnostic. Cytological results were as follows, nodular goiter comprised 83.3%, non-diagnostic samples 7.1%, papillary carcinoma 2.4%, atypia 2.4%, thyroglossal cyst 2.4%, and thyroiditis 2.4%. Conclusion: The findings are comparable in terms of sex, age and FNA cytologic diagnostic results to other studies. FNA cytology offered clinicians the possibility of early diagnosis of benign (>70%) and malignant (<5%) lesions. The test was an outpatient procedure, safe, time saving, cost effective and helped determine the course of therapy in the management of patients with thyroid nodules.

Diagnostic accuracy of fine needle aspiration cytology in patients undergoing thyroidectomy in Uganda: tertiary hospital experience

“…The female to male (F:M) ratio was 15.5:1 meaning that this is predominantly a disease of women. This was observed in related studies within the East African region 7,12 . In all patients the main presenting complaint was an anterior neck swelling with median time interval to presentation of 364 weeks (7 years) [ Table 2].…”

Bethesda reporting of thyroid FNACS with T3, T4, TSH correlation in a medical college of North Karnataka

“…In our study, most of the lesions were observed in females, correlating with studies by CK Sang et al, Gupta R et al, and Rupam et al, have similar findings. 8,9 Most lesions from our study were Benign of Bethesda category-II showing similar findings as Shukla et al 10 11,12 Cytologically, hurthle cells & granulomas (Figure 1) were demonstrated in hashimoto thyroiditis, some of the cases showed multinucleate giant cells.…”

Fine needle aspiration biopsy in low‐ and middle‐income countries

“…In one study from Kenya, benign thyroid nodules were accurately distinguished from malignant nodules, while the FNAB was best performed by cytopathologists. The authors of this study recognize, however, that this diagnostic excellence on the part of the cytopathologist requires considerable skill and technical experience 39 . In addition, the FNAB can provide material for ancillary testing of thyroid lesions.…”

“…The authors of this study recognize, however, that this diagnostic excellence on the part of the cytopathologist requires considerable skill and technical experience. 39 In addition, the FNAB can provide material for ancillary testing of thyroid lesions. For example, a survey of countries in the Gulf Cooperation Council highlighted that only less than 10% of indeterminate nodules were being sent for molecular testing, however interest for molecular testing for indeterminate thyroid FNAs to supplement diagnosis was much higher.…”