Fine Needle Aspiration Cytology and Diagnostic Pitfalls in Warthin’s Tumor with Necrotizing Granulomatous Inflammation and Facial Nerve Paralysis

Squamous Cell Carcinoma Arising in Warthin’s Tumour: A Case Report

“…A malignant change in a Warthin's tumour is suggested clinically by a recent history of a rapid enlargement of a longstanding mass [4] This was noted in the present case as well as in the patients which were described by Damjanov et al [9].…”

“…failure of FNAC to yield diagnostic oncocytes. In some cases, its detection is precluded by extensive necrosis of the oncocytic epithelium or by replacement of the oncocytic epithelium by a metaplastic mucinous or a squamous epithelium [4].…”

“…Warthin's tumour is more common in men, with a peak incidence in the seventh decade and it is associated with cigarette smoking. The tumour is usually an asymptomatic and a slow growing painless mass and it is bilateral in about 10% of the cases [1][2][3][4][5].…”

“…Sudden increase in its size is attributable to a malignant change or inflammation [1,2,4]. The malignant transformation of Warthin's tumour is extremely rare (0.3%).…”

“…The malignant transformation of Warthin's tumour is extremely rare (0.3%). The malignant transformation of its lymphoid component into malignant lymphoma is relatively common, whereas, an epithelial malignancy in Warthin's tumour is extremely rare [3,4]. Till date, only 32 cases of epidermoid carcinoma have been reported to arise in Warthin's tumour [3].…”