Findings in uterine biopsies obtained by laparotomy from bitches with unexplained infertility or pregnancy loss: An observational study

Mir, Fernando; Fontaine, Emmanuel; Albaric, Olivier; Greer, Marty; Vannier, Florence; Schlafer, Donald H.; Fontbonne, Alain

doi:10.1016/j.theriogenology.2012.09.005

Cited by 45 publications

(70 citation statements)

References 20 publications

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“…Regarding the hematological data, a relation between anemia and RF in the animals was observed when considering the erythrocytes (F 32.2, DF= 1.33, P<0.05, Figure 1a), hemoglobin levels (F = 32.8, DF = 1.33, P<0.05, Figure 1b), and the haematocrit (F = 35, DF = 1.33, P<0.05, Figure 1c (Greene, 2012). A previous work also did not find B. canis or CaHV-1 in maternal tissues of bitches with RF (Mir et al, 2013). Since dogs are vaccinated for CPV, RF associated with this disease is unlikely to occur due to mass population immunity (Givens and Marley, 2008).…”

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confidence: 72%

Abortion and fetal death in bitches due anemia caused by vector-borne diseases

Freire

Oliveira

Ferreira

et al. 2017

Arq. Bras. Med. Vet. Zootec.

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mentioning

confidence: 72%

Abortion and fetal death in bitches due anemia caused by vector-borne diseases

Freire

Oliveira

Ferreira

et al. 2017

Arq. Bras. Med. Vet. Zootec.

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“…; Mir et al. ). Vaginal cytological examination alone therefore cannot rule out uterine inflammation but may still be helpful in the diagnostic work‐up if signs of infection and inflammation such as largely increased numbers of bacteria, pus or bacteria engulfed by neutrophils are demonstrated in cases where the uterus and ovaries are normal by ultrasonography.…”

Section: Diagnostic Indicators Of Diseases Without Uterine Enlargementmentioning

confidence: 99%

“…The case history may be vague and includes infertility, subfertility or pregnancy loss (Mir et al. ). Many bitches with uterine inflammation have no signs of illness, and vaginal cytology is in most cases normal (Verstegen et al.…”

Section: Diagnostic Indicators Of Diseases Without Uterine Enlargementmentioning

confidence: 99%

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Diagnostic and Prognostic Markers for Uterine Diseases in Dogs

Hagman

2014

Reprod Domestic Animals

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Contents Common uterine diseases in female dogs include cystic endometrial hyperplasia (CEH), mucometra, hydrometra and pyometra. It is important in clinical practice to recognize pyometra because it is potentially life‐threatening due to the systemic illness induced by bacterial infection of the uterus. In contrast, the uterine content is sterile in CEH and mucometra/hydrometra, and clinical signs are mostly mild or absent. Optimal treatment depends on the type of uterine disease and its severity, but diagnosis and prognosis determination may be challenging and the diseases difficult to separate clinically. Diagnostic findings or biomarkers that may aid in the differentiation of the diseases are valuable, especially when several bitches are admitted with a fluid‐filled uterus during night‐time, and it has to be decided which patient to operate on first. Additionally, some variables may indicate outcome as measured by mortality or morbidity. If the uterus is not enlarged or fluid‐filled, detection of uterine disease can be even more difficult. In this study, clinically useful variables with possible diagnostic or prognostic value for uterine diseases in dogs are discussed.

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“…In contrast, cases of canine uterus infection and inflammation are very common (Watts et al 1998, Pretzer 2008, Fontaine et al 2009). Studies focusing on reliable prognostic factors, that might also be used to reach an early diagnosis of uterine diseases, have increased (Weiss et al 2004, Sant' Anna et al 2014, Mir et al 2013.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of physiological parameters of dogs submitted to uterine lymphatic mapping using patent blue V dye for anaphylaxis detection

et al. 2016

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RESUMO.-[Avaliação de parâmetros fisiológicos de cães submetidos ao mapeamento linfático uterino usando o corante azul patente V para a detecção de anafilaxia.] O mapeamento linfático tem sido realizado em humanos e cães. Embora inúmeros casos de anafilaxia já tenham sido relatados em humanos, não existem tais relatos em cães. O objetivo deste estudo foi identificar a ocorrência de reações adversas ao corante azul patente V em cadelas submetidas ao mapeamento linfático uterino, usando avaliações cardiovasculares e hematológicas. O experimento foi realizado em 14 cadelas mestiças, divididas igualmente em dois grupos (PBV-mapeamento linfático uterino e OEH; Controle -apenas OEH). Os animais foram submetidos a exames hematológicos e bioquímicos séricos no pré e pós-operató-rio (7 dias). O protocolo anestésico foi: sedação (morfina e acepromazina), indução (propofol), manutenção (isoflurano), analgesia trans-operatória (fentanil Lymphatic mapping has been performed in humans and dogs. Although several cases of anaphylaxis have been reported in humans, there are no such reports in dogs. The objective of this study was to identify the occurrence of adverse reactions to patent blue V dye in bitches undergoing uterine lymphatic mapping procedures using cardiovascular and hematological evaluations. The experiment was performed in 14 mongrel bitches without any reproductive disease, randomly assigned into two equal groups (PBV-uterine lynphatic mapping and OHE; Control -OHE only). The animals were submitted to pre-and postoperative hematological and serum biochemistry exams (7 days). The anesthetic protocol was: sedation (morphine and acepromazine), induction (propofol), maintenance (isoflurane), transoperative analgesia (fentanyl). Systolic blood pressure was monitored throughout the procedure and arterial blood gas analysis was performed immediate pre and postoperatively. For lymphatic mapping was injected patent blue V in the uterine wall, 10 minutes before OEH. Comparisons between the pre-and postoperative parameters within the same animal were performed using the Wilcoxon-Mann-Whitney test. To compare the values between control and PBV group was obtaining the difference between the pre and post of each group, subjected to the Mann-Whitney test (significance of 5%). Differences were observed (P<0.05) between the pre-and postoperative evaluations in the PBV (total protein and the albumin serum), in both groups (arterial partial pressure of oxygen) and in the Control (arterial oxygen saturation). There were no signs of adverse reactions to the patent blue V dye in the healthy bitches submitted to lymphatic uterine mapping.INDEX TERMS: Uterine lymphatic mapping, patent blue V dye, anaphylaxis, hypersensitivity, bitches, vital dye.

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Findings in uterine biopsies obtained by laparotomy from bitches with unexplained infertility or pregnancy loss: An observational study

Cited by 45 publications

References 20 publications

Abortion and fetal death in bitches due anemia caused by vector-borne diseases

Abortion and fetal death in bitches due anemia caused by vector-borne diseases

Diagnostic and Prognostic Markers for Uterine Diseases in Dogs

Evaluation of physiological parameters of dogs submitted to uterine lymphatic mapping using patent blue V dye for anaphylaxis detection

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