Fifteen years of cutaneous and mucocutaneous leishmaniasis in Bolivia: a retrospective study

David, C.; Dimier-David, L.; Vargas, Fernando; Torrez, Miguel; Dedet, Jean-Pierre

doi:10.1016/0035-9203(93)90398-a

Cited by 39 publications

(15 citation statements)

References 5 publications

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“…These activities placed men in a condition of higher exposure to sandfly bites due to the agricultural nature of their work. 18 Our findings of incidence and prevalence identify La Montaña as the locality with the highest risk of leishmaniasis in the study area. This must be related to the specific characteristics of its geographic location; that is, a high altitude and a jungle environment that favors the presence of vectors and reservoirs available for the transmission of these infections.…”

Section: Discussionmentioning

confidence: 63%

Epidemiologic characterization of American cutaneous leishmaniasis in an endemic region of eastern Venezuela.

Jorquera

Ledezma²,

Sousa³

et al. 1998

The American Journal of Tropical Medicine and Hygiene

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Abstract. The status of American cutaneous leishmaniasis was investigated from 1985 to 1991 to provide an epidemiologic characterization of the disease in Bergantin, a rural community in the northeastern part of Anzoátegui State, Venezuela. The study revealed the presence of the infection during the period analyzed, with an average incidence of 50.2 cases per 10,000 inhabitants and this number has increased 1.5 times during the last two years. Three villages where clinical cases had been recorded were selected for a comparison of their prevalence data. These villages comprise the human population in the high and low altitude limits of Bergantin. Immunologic assessment of the inhabitants used two different antigen preparations to examine responses to parasites associated with the cutaneous and visceral forms of the disease. The leishmanin skin test (LST) was used in a sample of 276 individuals (46.3% of the inhabitants) and resulted in an overall positivity of 16.7%. The percentage of LST positivity varied with age and sex, yet analysis of this response and the prevalence for each village reflected the specific characteristics of these localities. La Montaña, situated at 800 meters above sea level, had the highest prevalence (800 cases per 10,000 inhabitants) and the most positive LST response (21.2%) in comparison with the two other villages situated at a lower altitude (300 meters above sea level).Venezuela is one of the South American countries where American cutaneous leishmaniasis (ACL) is increasing. However, the epidemiologic characteristics of the disease are mostly unknown. Estimates of the number of cases are frequently unreliable due to local difficulties in diagnosis and the frequency of subclinical infections. 1 In general, a better understanding of the epidemiology of ACL is important so that effective control measures may be applied.The geographic distribution of ACL in Venezuela covers 21 of its 23 territorial divisions. It has been shown that these ACL-affected regions present foci with different degrees of endemicity, but only the infections detected in the western and central regions have been systematically described. [1][2][3][4][5] Presently, little is known about the epidemiology of leishmaniasis in the eastern region of the country.The general purpose of the study was to determine the distribution, prevalence, and risk factors for the disease within the endemic areas of the Turimiquire Mountains in the northeastern states of Venezuela. MATERIALS AND METHODSStudy area. This study was carried out in the territory of Bergantin located in the southwestern area of the Turimiquire Mountains between latitudes 10Њ03Ј30Љ'' and 10Њ00Ј17ЉN and longitudes 64Њ20Ј18Љ and 64Њ23Ј20ЉW in the Anzoátegui State of Venezuela. Bergantin comprises 36 villages within a total area of 630 km 2 . Of these, approximately 61 km 2 , including the villages of La Montaña (800 meters above sea level), La Panela (300 meters above sea level), and El Poblado (300 meters above sea level) (Figure 1), were studied. These villag...

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Section: Discussionmentioning

confidence: 63%

Epidemiologic characterization of American cutaneous leishmaniasis in an endemic region of eastern Venezuela.

Jorquera

Ledezma²,

Sousa³

et al. 1998

The American Journal of Tropical Medicine and Hygiene

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“…4 Muco-CL is estimated to develop as a complication of L viannia subgenus CL in 5% to 20% of untreated patients living in areas where leishmaniasis is endemic. 5,6 More than 90% of CL cases occur in Iran, Afghanistan, Syria, Saudi Arabia, Brazil, and Peru. 2 Leishmaniasis is extremely common in many regions of the Americas.…”

Section: Epidemiologymentioning

confidence: 99%

New World cutaneous leishmaniasis: Updated review of current and future diagnosis and treatment

Mitropoulos¹,

Konidas²,

Durkin-Konidas³

2010

Journal of the American Academy of Dermatology

128

104

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“…New world cutaneous leishmaniasis of the Viannia complex can also present with concomitant or delayed mucosal involvement in 5-20% of cases 8. This typically manifests as nasal symptoms such as congestion and secretions, and can progress to local destruction of nasal, palatal, pharyngeal, and laryngeal tissue.…”

Section: Answersmentioning

confidence: 99%

An ulcer that will not heal

Clegg

Hall

Lockwood

2018

BMJ

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Fifteen years of cutaneous and mucocutaneous leishmaniasis in Bolivia: a retrospective study

Abstract: This paper present the results of a retrospective study of cases of cutaneous and mucocutaneous leishmaniasis in Bolivia between 1975 and 1991. The total number of cases reported was 4058, 739 of which were mucous. Three different areas of endemic leishmaniasis are defined in Bolivia.

Cited by 39 publications

References 5 publications

Epidemiologic characterization of American cutaneous leishmaniasis in an endemic region of eastern Venezuela.

Epidemiologic characterization of American cutaneous leishmaniasis in an endemic region of eastern Venezuela.

New World cutaneous leishmaniasis: Updated review of current and future diagnosis and treatment

An ulcer that will not heal

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