New World cutaneous leishmaniasis: Updated review of current and future diagnosis and treatment

Mitropoulos, Panagiotis; Konidas, Pete; Durkin-Konidas, Mindy

doi:10.1016/j.jaad.2009.06.088

Cited by 128 publications

(112 citation statements)

References 92 publications

(124 reference statements)

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“…It encompasses visceral and tegumentary forms, including cutaneous and mucocutaneous forms. 1,2 American tegumentary leishmaniasis (ATL) is an important public health problem in Latin America, and the mucosal form is the most severe presentation. Also known as "spundia," mucosal leishmaniasis (ML) is characterized by destructive lesions of oral, nasal, laryngeal, and pharyngeal cavities.…”

Section: Introductionmentioning

confidence: 99%

Efficacy and Safety of Liposomal Amphotericin B for the Treatment of Mucosal Leishmaniasis from the New World: A Retrospective Study

Cunha¹,

Leão²,

Soler³

et al. 2015

The American Society of Tropical Medicine and Hygiene

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Abstract. The standard treatment of mucosal leishmaniasis (ML) is pentavalent antimonials, agents with serious adverse effects. Alternative agents include amphotericin B deoxycholate and liposomal amphotericin B. We performed a retrospective study including 29 patients treated with liposomal amphotericin B, most of whom had comorbidities, history of previous treatment of ML, and contraindications to the use of antimonial pentavalent or amphotericin B deoxycholate. We observed a cure rate of 93.1%. Kidney failure was the most important side effect, reported in five patients (17.2%). This study showed a good efficacy and safety profile of liposomal amphotericin B in patients with ML and contraindications to the use of other agents.

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Section: Introductionmentioning

confidence: 99%

Efficacy and Safety of Liposomal Amphotericin B for the Treatment of Mucosal Leishmaniasis from the New World: A Retrospective Study

Cunha¹,

Leão²,

Soler³

et al. 2015

The American Society of Tropical Medicine and Hygiene

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“…Indeed, differential diagnoses including the cutaneous larva migrans and cutaneous leishmaniasis caused by other arthropods should be excluded [15] . In addition, a Tunga flea invades the host's skin may cause a furuncular nodule which can also resemble as furuncular myiasis.…”

Section: Discussionmentioning

confidence: 99%

First report of furuncular myiasis caused by the larva of botfly, Dermatobia hominis, in a Taiwanese traveler

Wang

Chao

et al. 2013

Asian Pacific Journal of Tropical Biomedicine

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“…Mortality is estimated at 20,000-30,000 annually, second only to malaria for diseases caused by a protozoan [37]. More than 90 % of New World cutaneous disease originates from Brazil and Peru; Old World disease originates mostly from Iran, Afghanistan, Syria, and Saudi Arabia [38,39]. New World disease is typically limited to Central and South America; disease is uncommon in the USA, although occasional case reports have come from Texas and Oklahoma [40].…”

Section: Epidemiologymentioning

confidence: 99%

“…The papule enlarges and forms larger nodules and plaques with indurated borders that may ulcerate. Cutaneous leishmaniasis can be caused by numerous species in both Old World and New World disease [39]. Diffuse (anergic) cutaneous leishmaniasis (Fig.…”

Section: Clinical Presentationmentioning

confidence: 99%

Got the Travel Bug? A Review of Common Infections, Infestations, Bites, and Stings Among Returning Travelers

2016

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The popularity of international travel continues to increase among Americans, even though they often experience subsequent illness on return from their journey. The pathogens responsible are not necessarily endemic to the destination itself but are often the result of poor sanitary conditions or activities engaged in while away. Skin disease ranks third among all medical concerns in returning travelers. This review addresses the pathogenesis, epidemiology, clinical presentation, and treatment of the most common skin diseases in returning travelers: insect bites and bedbugs, cutaneous larva migrans, scabies, tungiasis, myiasis, leishmaniasis, viral exanthems, and marine envenomation. Primary care physicians and dermatologists should be familiar with these illnesses and a general approach to their evaluation and management. Key PointsArthropod assault and infestation is a source of significant morbidity in returning travelers.Travelers should bring proper protective clothing and insect repellant when travelling to areas where biting insects are vectors of disease.Travelers should be acquainted with the hazards associated with local marine life if they plan on entering the water.

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New World cutaneous leishmaniasis: Updated review of current and future diagnosis and treatment

Cited by 128 publications

References 92 publications

Efficacy and Safety of Liposomal Amphotericin B for the Treatment of Mucosal Leishmaniasis from the New World: A Retrospective Study

Efficacy and Safety of Liposomal Amphotericin B for the Treatment of Mucosal Leishmaniasis from the New World: A Retrospective Study

First report of furuncular myiasis caused by the larva of botfly, Dermatobia hominis, in a Taiwanese traveler

Got the Travel Bug? A Review of Common Infections, Infestations, Bites, and Stings Among Returning Travelers

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