Fibroxanthosarcoma of bone

Newland, R. C.; Harrison, Maria; Wright, Robert F.

doi:10.3109/00313027509094410

Cited by 28 publications

(5 citation statements)

References 8 publications

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“…The characteristic features of the MFH at the spine, in addition to the bony destruction in the vertebrae, were frequently huge paraspinal soft tissue mass at contiguous levels, with a tendency to extensively invade of the medical literatures published in English, 17 cases with histologically confi rmed primary MFH of the spine have been reported in case reports since 1976. [4][5][6][7][8][9][10][11][12][13][14][15][16][17] The age distribution and mean age of the spine were consistent with MFH in the other bones. 8,27,28 The anatomic distribution of MFH at the spine in the authors' and literature groups showed predominantly thoracic and/or lumbar spine involvement, followed by sacral vertebrae.…”

Section: Resultsmentioning

confidence: 60%

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Malignant Fibrous Histiocytoma of the Spine

Teng¹,

Yang²,

Wei³

et al. 2011

Spine

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The MFH of the spine tends to extensively invade paraspinal structures at multiple spinal levels, with aggressive osteolytic destruction in the vertebrae, resulting to local huge mass, radiculopathy, and myelopathy. Regardless of recent advancements in the diagnosis, treatment methods, and adjuvant therapies, for its biologically aggressive nature, it frequently recurs at the primary site and metastasizes. It has a worse prognosis than that of MFH in other sites.

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Section: Resultsmentioning

confidence: 60%

“…These were compared with the pooled results of 17 cases in total that were reported in the literature to date. [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] …”

Section: Spine Malignant Fibrous Histiocytoma Surgery Chemotherapymentioning

confidence: 99%

Malignant Fibrous Histiocytoma of the Spine

Teng¹,

Yang²,

Wei³

et al. 2011

Spine

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“…Primary MFH of the spine is an extremely rare entity that was first reported in 1975 by Newland et al 17 Since its initial description, there have only been 34 cases reported in the literature (Table 1). We report a case of MFH in the thoracic spine with aortic infiltration that was managed with en bloc spondylectomy and aortic resection with graft reconstruction.…”

Section: Discussionmentioning

confidence: 99%

“…[1][2][3]5,6,8,[12][13][14][16][17][18]20,21,[24][25][26] Since the first description of spondylectomy for a giant cell tumor of the lumbar spine in 1966, total spondylectomy has become a viable treatment option for many primary spinal tumors. 23,27 Tomita and colleagues in 1994 subsequently described a method of total en bloc spondylectomy, which minimized the intratumoral cutting edge to the bilateral pedicles.…”

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confidence: 99%

En bloc spondylectomy for primary malignant fibrous histiocytoma of the thoracic spine with aortic involvement: case report

Somasundaram¹,

Wicks²,

Lata³

et al. 2015

SPI

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In this article, the authors describe a 48-year-old man who initially presented with progressively worsening back pain. Magnetic resonance imaging revealed a soft-tissue mass involving the T10–11 vertebral bodies with extension anteriorly into the aorta as well as epidural extension without spinal cord compression. A biopsy of the mass showed findings consistent with a malignant fibrous histiocytoma (MFH). A total en bloc spondylectomy with resection and reconstruction of the involved aorta using a vascular graft was performed. The patient received postoperative radiation therapy and is neurologically intact at 18 months postoperatively. To the authors' knowledge, this is the first reported case of a spinal MFH resection with aortic reconstruction.

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“…Neuroimaging showed purely lytic, expansive lesions with well-defined margins, usually with cortical destruction and soft-tissue invasion, but without periosteal reaction or new bone formation. The prognosis for primary spine MFH is dismal, and about half of the patients were dead within 15 months [ 8 , 9 ].…”

Section: Discussionmentioning

confidence: 99%

Storiform-Pleomorphic Type of Multifocal Malignant Fibrous Histiocytoma of the Lumbar Spine

et al. 2014

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Patient: Male, 67Final Diagnosis: Malignant fibrous histiocytomaSymptoms: Back pain • leg weakness • weight lossMedication: —Clinical Procedure: —Specialty: —Objective:Rare diseaseBackground:We present the extremely rare case of a 67-year-old male with malignant fibrous histiocytoma, arising in the lumbar spine, demonstrated with radiological and pathological studies.Case Report:The patient and his relatives refused open surgical approach and we performed transpedicular vertebral corpus biopsy and vertebroplasty under spinal anesthesia. His pathological result was malignant fibrous histiocytoma. The spine is a very uncommon site for malignant fibrous histiocytoma.Conclusions:The management of malignant fibrous histiocytoma relies on the combination of maximum decompression surgery, chemotherapy and radiotherapy. Total removal is unrealistic and diagnosis is difficult. The prognosis in terms of continuing neurological deficit after surgery appears to be poor.

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Fibroxanthosarcoma of bone

Cited by 28 publications

References 8 publications

Malignant Fibrous Histiocytoma of the Spine

Malignant Fibrous Histiocytoma of the Spine

En bloc spondylectomy for primary malignant fibrous histiocytoma of the thoracic spine with aortic involvement: case report

Storiform-Pleomorphic Type of Multifocal Malignant Fibrous Histiocytoma of the Lumbar Spine

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