En bloc spondylectomy for primary malignant fibrous histiocytoma of the thoracic spine with aortic involvement: case report

Abstract

<jats:p>In this article, the authors describe a 48-year-old man who initially presented with progressively worsening back pain. Magnetic resonance imaging revealed a soft-tissue mass involving the T10–11 vertebral bodies with extension anteriorly into the aorta as well as epidural extension without spinal cord compression. A biopsy of the mass showed findings consistent with a malignant fibrous histiocytoma (MFH). A total en bloc spondylectomy with resection and reconstruction of the involved aorta using a vascular graft was performed. The patient received postoperative radiation therapy and is neurologically intact at 18 months postoperatively. To the authors' knowledge, this is the first reported case of a spinal MFH resection with aortic reconstruction.</jats:p>

Carbon ion radiotherapy for unresectable primary undifferentiated pleomorphic sarcoma of the 11th thoracic spine: a case report

“…In addition, the authors reported that en bloc resection at wide margins significantly improved prognosis 3) . Therefore, en bloc resection with negative surgical margins is recommended for spinal UPS 2,3,5) . However, resection with a wide margin was considered impossible because of the extravertebral extension of the tumor in our In a report by Matsumoto et al of 47 patients with unresectable spinal sarcoma (excluding the sacrum) treated with carbon ion radiotherapy, the median survival was 44 months, with a 5-year local control rate of 79% and a 5-year survival of 52% 9) .…”

“…Spinal UPS is often slow-growing and appears as a complete osteolytic lesion with clear margins, destruction of the bone cortex, and extension into the surrounding soft tissue. Bone destruction is characterized by the absence of a periosteal reaction or new bone 2 , 3 , 4 , 5 ) . Similar findings were observed in this case.…”

“…In addition, the authors reported that en bloc resection at wide margins significantly improved prognosis 3 ) . Therefore, en bloc resection with negative surgical margins is recommended for spinal UPS 2 , 3 , 5 ) . However, resection with a wide margin was considered impossible because of the extravertebral extension of the tumor in our case; hence, carbon ion radiotherapy was chosen.…”

Palliative Care of Malignant Fibrous Histiocytoma of Spine with Cord Compression and Multiple Bone Metastases Treated by Multidisciplinary Therapy: Case Report

“…Bone destruction is characteristically not accompanied by periosteal reaction or new bone formation [4]. Treatment includes irradiation, embolization, and surgery with en-bloc resection being the only curative option [4,6]. It is known that MFH can be transplanted to the surgeon during operation [7] so special precautions are recommended.…”