Fibrous Membranes Electrospinning from Acrylonitrile‐Based Polymers: Specific Absorption Behaviors and States of Water

Wan, Ling‐Shu; Xu, Zuhua; Jiang, Hongliang

doi:10.1002/mabi.200600017

Cited by 18 publications

(15 citation statements)

References 61 publications

(73 reference statements)

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“…With our optimized electrospinning parameters reported previously, 31 beads-free and relatively uniform nanofibers were electrospun onto polymerdense membranes to create nanostructured surfaces. The electrospinning process is schematically illustrated in Figure 1.…”

Section: Fabrication Of Model Surfaces Covered With Random or Alignedmentioning

confidence: 99%

“…Both polyacrylonitrile (PAN) with relatively poor biocompatibility and poly[acrylonitrile-co-(N-vinyl-2pyrrolidone)] (PANCNVP) with excellent biocompatibility were used for preparing nanofiber or underlying membrane. 31,32 In view of the fact that blood platelets play a crucial role in coagulation and that platelets adhesion has been generally applied to evaluate the hemocompatibility of materials, the adhesion of blood platelets on the resultant nanostructured surfaces was carefully studied. It was found that the generation of nanofibers on polymer surface could greatly promote the adhesion of blood platelets.…”

Section: Introductionmentioning

confidence: 99%

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Polymer surfaces structured with random or aligned electrospun nanofibers to promote the adhesion of blood platelets

Wan

2008

J Biomedical Materials Res

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Fibrous membranes (nonwoven meshes) prepared via electrospinning technique have great potential in tissue engineering. This work is the first study on the behaviors of blood platelets at the nanostructured surface generated by electrospinning. Poly[acrylonitrile-co-(N-vinyl-2-pyrrolidone)] (PANCNVP) that shows excellent antiplatelet adhesion ability was directly electrospun onto its dense membrane surface. Polyacrylonitrile (PAN) samples were used as controls. The depth as well as the density of the nanofibers can be easily controlled. The results showed that the PANCNVP dense membrane certainly suppressed the activation and adhesion of platelets. However, whether the nanofibers and underlying membranes were composed of PAN or PANCNVP, the nanostructured surfaces promoted the activation, adhesion, and orientation of platelets. It was also found that, if the space between fibers was too large or the depth of fibers was too small, the nanostructured surface did not change the property of antiplatelet adhesion of PANCNVP. The promotion of activation and adhesion of platelets was obviously due to the presence of nanofibers, which induced the changes of surface topography and charge.

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Section: Fabrication Of Model Surfaces Covered With Random or Alignedmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Polymer surfaces structured with random or aligned electrospun nanofibers to promote the adhesion of blood platelets

Wan

2008

J Biomedical Materials Res

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“…With our optimized electrospinning parameters reported previously,31 beads‐free and relatively uniform nanofibers were electrospun onto polymer‐dense membranes to create nanostructured surfaces. The electrospinning process is schematically illustrated in Figure 1.…”

Section: Resultsmentioning

confidence: 99%

“…In this work, surfaces with random or aligned nanofibers were successfully created on versatile polymer membranes by electrospinning technique. Both polyacrylonitrile (PAN) with relatively poor biocompatibility and poly[acrylonitrile‐ co ‐( N ‐vinyl‐2‐pyrrolidone)] (PANCNVP) with excellent biocompatibility were used for preparing nanofiber or underlying membrane 31, 32. In view of the fact that blood platelets play a crucial role in coagulation and that platelets adhesion has been generally applied to evaluate the hemocompatibility of materials, the adhesion of blood platelets on the resultant nanostructured surfaces was carefully studied.…”

Section: Introductionmentioning

confidence: 99%

Controlled degradation of natural rubber and modification of the obtained telechelic oligoisoprenes: Preliminary study of their potentiality as polyurethane foam precursors

Saetung¹,

Rungvichaniwat²,

Campistron³

et al. 2010

J of Applied Polymer Sci

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Telechelic oligoisoprenes were successfully prepared by the selective controlled degradation of natural rubber, a renewable source, via epoxidation and cleavage reactions. The molar mass of the oligoisoprene product obtained depends on the degree of epoxidation of the starting materials. The chemically modified structures obtained via epoxidation, hydrogenation, and ring opening of epoxide groups were also studied, and the chemical structures and thermal properties of the oligoisoprene products were determined. Moreover, the preliminary study of preparation of hydroxytelechelic natural rubber (HTNR)-based polyurethane foam was performed. A novel HTNR-based polyurethane foam was successfully prepared and its thermal properties were investigated and the results indicated that the HTNR-based polyurethane foam has a good low temperature flexibility.

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“…This technique has been shown to fabricate scaffolds to membranes as a function of the substrate exposure time to the threading process. 36,37 The essential difference between the ability for forming fibers via electrosprays to electrospinning is that the former has the ability to locate the fibers in selected areas on a substrate while the latter has no control. However the latter has been shown to form controlled fiber orientated structures 38 which are of most interest for a range of applications where for example living cells could be encouraged to proliferate along the fiber in a controlled direction.…”

Section: Electrospinning (Es)mentioning

confidence: 99%

Pressure-Assisted Spinning: A Unique and Versatile Approach for Directly Fabricating Membranes With Micro- And Nanofibers

Arumuganathar

Jayasinghe

2007

NANO

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Fibers are structurally interesting components most useful in a range of applications spanning the physical and life science areas of research. These membrane (scaffold) forming fibers have been explored in applications ranging from microfilteration to advanced biological investigations in tissue engineering to controlled and targeted drug delivery. One such robust fiber generation approach investigated for over a century, which has recently been exploited, is the well-established threading process referred to as electrospinning. In this technique, single-or multi-phase media are charged within a conducting needle and later exposed to an electric field which promotes the formation of a continuous micro-to nanosized fiber(s) which over a period of collection time has been reported for forming scaffolds and membranes. This process has been explored for a wide range of polymer composite-based materials and the technique has now reached the point where it has moved into industrial production. We report here as a first example a comparable fiber to membrane fabrication approach completely driven by the coupling of a coaxial needle system with a pressure. We refer to this novel methodology as pressure-assisted spinning (PAS) where the hazardous element of high voltage (as in the case of electrospinning) is nonexistent. Hence, our discovery introduces both a directly competing fiber, scaffold to membrane fabrication approach, which is versatile and has no associated hazards as those in electrospinning. Furthermore as our technique is nonelectric field driven, the media spun into fibers could have a high electrical conductivity, which in this case has no effect on the stability in processing near-uniform fibers/scaffolds to membranes. The fabricated fibers and membranes generated by means of this approach could directly be used for a plethora of applications spanning the engineering and biological areas of research.

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Fibrous Membranes Electrospinning from Acrylonitrile‐Based Polymers: Specific Absorption Behaviors and States of Water

Cited by 18 publications

References 61 publications

Polymer surfaces structured with random or aligned electrospun nanofibers to promote the adhesion of blood platelets

Polymer surfaces structured with random or aligned electrospun nanofibers to promote the adhesion of blood platelets

Controlled degradation of natural rubber and modification of the obtained telechelic oligoisoprenes: Preliminary study of their potentiality as polyurethane foam precursors

Pressure-Assisted Spinning: A Unique and Versatile Approach for Directly Fabricating Membranes With Micro- And Nanofibers

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