Fibrous Complexes of Deoxyribonucleic Acid with Certain Globular Proteins. Role of Divalent Metal Ions in the Organization of Nucleoprotein Structures^*

Age-Related Alterations in the Structure of Nucleoprotein

“…Changes in the proportions of 'highlysine' to 'high-arginine' histones may thus have a part in determining which regions of the genome are covered by histone. Divalent metal ions have been shown to play a significant role in the binding of basic proteins to DNA [K abat, 1967;Latt and Sober, 1967;Shin and Eichhorn, unpublished results], and as our results show, they appear to be active selectively in binding 'high-arginine' histones. Changes in concentration of such cations may thus cause changes in histone com position in nucleoprotein.…”

Resonance Raman spectra of methemoglobin derivatives. Selective enhancement of axial ligand vibrations and lack of an effect of inositol hexaphosphate

“…Even the pyrrole-nitrogen-Fe vibrations are not visibly enhanced, SU]gesting that the electronic transition whidl is respcnsible for the absorption band at 6400 ~ in M3t:Hb N 'j is different fran the electrc:nic transition whidl is responsible for the dlarge transfer band in MnETP. This cx:mclusion is supported by polarization studies of the abso.rptian spectra of single ccystals of .r-~t:Hb N; (Kabat, 1967) , and MetMb N'j (Eaton and Hoc.luitrasser, 1968) , which indicate that a z-polarized electronic transition is respcnsible for the absorption band at 6400 ~, and the Ml> spec-b:un of ~t.Mb N'j which 500ws a negative extretrum due to the 6400 ~ absorption band (Vickery, et al, .1976) • In oontrast, the M:D spect....""Un of the charge transfer band of M1ETP exhibits a Faraday A term, indicating a de9enerate, x, y-polarized electronic transition (Boucher, 1972;Asher, 1976). z It is less likely that the band results fran a d + d transition, because its nolar absorptivity (E "' 10 3 } is an order of magnitude higher than the rrolar ( abso.rptivity ~cted ford+ d transitions (Smith and Williams, 1970).…”

Conformational transitions and vibronic couplings in acid ferricytochrome c: a resonance Raman study

“…which contains an unresolved z-polarized electronic transition (Kabat, 1967;Eaton & Hochstrasser, 1968). The situation with the x.y'-polarized charge transfer is somewhat more complex.…”