Fibrosarcoma of the maxillary sinus

Abstract

Fibrosarcoma arising in the sinonasal cavities are very rare. By the time of clinical diagnosis, they are usually advanced. Lack of adequate surgical margins predisposes these patients to tumor recurrences. Most common sites are the extremities, with only one percent of fibrosarcoma arising in the head and neck area. The imaging features of these tumors reflect their aggressive behavior. We report the case of a maxillary sinus fibrosarcoma in a 16 year-old male patient. Neoadjuvant chemotherapy, medial maxillectomy, adjuvant chemotherapy and subsequent external irradiation was perfomed.

Central Primary Fibrosarcoma Maxilla - A Rare Presentation

“…Patients mostly present with complain of swelling in jaw with or without pain. Other complaints are loosening of teeth, trismus, fracture and paresthesia [3,5,6].…”

“…Characteristically cells are spindle with elongated oval to round hyperchromatic nuclei, varying in size. Myxomatous, pseudomyxomatous and cartilaginous areas may also be noted [1][2][3][4].…”

“…A Primary vs. secondary site of origin and histological grading, play an important role in the prognosis of FS. Secondary FS usually have an aggressive course [3,8,18]. A difference in clinical course between FS of jaw and its long bone counterpart has been reported by many authors.…”

“…It mostly accounts for 1-3% of adult sarcomas [1]. It is more frequently seen in soft tissue but primary intraosseous origin has been described in 5% of all cases [2,3]. It rarely affects head and neck region (10%).…”

“…Maxilla is rarely involved and accounts for only 0 to 6.1% cases [5]. Involvement of maxillary antrum is rarely seen [3]. FS of jaw can be periosteal (peripheral) or endosteal (central) [4].…”