Sinonasal fibrosarcoma: analysis of the Surveillance, Epidemiology, and End Results database

Patel, Tapan D.; Carniol, Eric T.; Vázquez, Alejandro; Baredes, Soly; Liu, James K.; Eloy, Jean Anderson

doi:10.1002/alr.21639

Cited by 20 publications

(27 citation statements)

References 31 publications

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“…In the current study, we identified 237 cases of malignant fibrous neoplasms of long bone based on the SEER database from 1973 to 2015. The OS and CSS rates at 5 years were 39.7 and 60.3%, respectively, while the previous study results showed that the OS and CSS of sinonasal fibrosarcoma were 71.7 and 77.8%, respectively [13].…”

Section: Discussioncontrasting

confidence: 57%

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Malignant fibrous neoplasms of long bones: analysis of the surveillance, epidemiology, and end results database from 1973 to 2015

Huang

Hong

Meng

et al. 2020

BMC Musculoskelet Disord

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Background: Malignant fibrous neoplasms (MFN) of long bones are rare lesions. Moreover, the prognostic determinants of MFN of long bones have not been reported. This study aimed to present epidemiological data and analyse the prognostic factors for survival in patients with MFN. Materials and methods: The Surveillance, Epidemiology, and End Results (SEER) programme database was used to screen patients with malignant fibrous neoplasms (MFN) of long bones from 1973 to 2015, with attention to fibrosarcoma, fibromyxosarcoma, periosteal fibrosarcoma and malignant fibrous histiocytoma. The prognostic values of overall survival (OS) and cancer-specific survival (CSS) were assessed using the Cox proportional hazards regression model with univariate and multivariate analyses. The Kaplan-Meier method was used to obtain OS and CSS curves. Results: A total of 237 cases were selected from the SEER database. Malignant fibrous histiocytoma was the most common form of lesion in long bones. Multivariate analysis revealed that independent predictors of OS included age, stage, tumour size and surgery. Age, stage, tumour size and surgery were also independent predictors of CSS. Additionally, the most significant prognostic factor was whether metastasis had occurred at the time of initial diagnosis. Conclusion: Among patients with MFN of long bones, age (> 60 years), tumour size (> 10 cm), distant stage, and non-surgical treatment are factors for poor survival.

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Section: Discussioncontrasting

confidence: 57%

“…These tumours can infiltrate adjacent tissues and metastasize distally [13][14][15][16][17][18][19]. However, the outcome and prognosis of patients with MFN of long bones have not been reported because of its rarity.…”

Section: Discussionmentioning

confidence: 99%

Malignant fibrous neoplasms of long bones: analysis of the surveillance, epidemiology, and end results database from 1973 to 2015

Huang

Hong

Meng

et al. 2020

BMC Musculoskelet Disord

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“…1,2 The paranasal sinus is one of the rarest locations for fibrosarcoma, with only a few cases having been reported in the literature since the year 2000, [1][2][3][4][5][6] although there have been comprehensive reviews on the treatment results and demographic and clinicopathological features of paranasal sinus fibrosarcoma. 7,8 The tissue origin of paranasal sinus fibrosarcoma seems to be the periosteum rather than mucosal connective tissue. 9 Paranasal sinus fibrosarcoma is commonly seen in middle-aged patients, with both genders being equally affected.…”

Section: Introductionmentioning

confidence: 99%

“…9 Paranasal sinus fibrosarcoma is commonly seen in middle-aged patients, with both genders being equally affected. 7 It can be further divided into infantile type and adult type, 4,10 and in routine clinical practice, adult-type sinonasal fibrosarcoma is easy to misdiagnose as other neoplasms because of its rarity and non-specific symptomatology. 2,7 Additionally, although basic information on this disease has been reported, there are only limited studies examining the imaging characteristics of paranasal sinus fibrosarcoma.…”

Section: Introductionmentioning

confidence: 99%

Fibrosarcoma arising in the paranasal sinus: a clinicopathological and radiological analysis

Zeng

Liu

et al. 2018

Dentomaxillofacial Radiology

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“…Sinonasal teratocarcinosarcoma is an extremely rare and highly aggressive malignant neoplasm, with complex components of mesenchymal, epithelial, and neuroectodermal elements; it is not easy to forecast its trend of development and prognosis owing to its uncertain clinical behavior [ 6 ]. Other histological tumor types reported in the sinonasal tract include Ewing’s sarcoma/PNET, malignant fibrous histiocytoma, chondrosarcoma and osteosarcoma, fibrosarcomas, leiomyosarcomas, and synovial sarcoma [ 7 – 11 ].…”

Section: Introductionmentioning

confidence: 99%

Treatment Outcomes and Prognostic Factors of Adult Sinonasal Sarcomas: A Single-Institution Case Series

et al. 2018

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BackgroundThe purpose of this study was to investigate the treatment outcomes and evaluate the prognostic factors of adult sinonasal sarcomas.Material/MethodsA retrospective review was performed on consecutive patients with adult sinonasal sarcomas treated in our institution from 2005 to 2016. The Kaplan-Meier method was used to evaluate local recurrence-free survival (LRFS), distant metastases-free survival (DMFS), and overall survival (OS). Univariate and multivariate analyses using Cox proportional hazard models were performed to determine the prognostic factors associated with survival outcomes.ResultsA total of 49 patients were followed up for 6–122 months, with a median time of 36 months. The 5-year LRFS, DMFS, and OS rates of all patients were 68.3%, 62.8%, and 43.2%, respectively. The results of univariate analysis revealed that patients with an advanced stage of primary tumor and those who received incomplete surgical resection had worse LRFS (p=0.013; p=0.026). Patients with the histological type rhabdomyosarcoma (RMS) and existing regional lymph node metastasis had worse DMFS (p=0.000; p=0.001). The histological type RMS, advanced stage of primary tumor, existing regional lymph node metastasis, and receiving incomplete surgical resection had an unfavorable effect on OS (p=0.001; p=0.002; p=0.008; p=0.011). The results of multivariate analysis showed that histological type and degree of surgical resection were the independent prognostic factors for OS.ConclusionsOur results suggest that the histological type RMS and receiving incomplete surgical resection are independent prognostic factors for worse OS.

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Sinonasal fibrosarcoma: analysis of the Surveillance, Epidemiology, and End Results database

Abstract: SNFS is a rare entity. This study represents the largest series of SNFS to date. The mainstay of treatment for this tumor is surgical resection with or without radiotherapy.

Cited by 20 publications

References 31 publications

Malignant fibrous neoplasms of long bones: analysis of the surveillance, epidemiology, and end results database from 1973 to 2015

Malignant fibrous neoplasms of long bones: analysis of the surveillance, epidemiology, and end results database from 1973 to 2015

Fibrosarcoma arising in the paranasal sinus: a clinicopathological and radiological analysis

Treatment Outcomes and Prognostic Factors of Adult Sinonasal Sarcomas: A Single-Institution Case Series

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