Fibromyxoma of bone

Abstract

We report two cases of fibromyxoma, one affecting the iliac crest and the second involving the proximal shaft of the tibia. Fibromyxoma is a rare neoplasm related to benign fibrous tumors and is characterized by exuberant, extracellular, ground substance production. Its histologic appearance is benign and distinctive and can be readily distinguished from that of myxoid chondrosarcoma or chondromyxoid fibroma. The radiographic picture is, however, difficult to interpret, and the entity can be easily mistaken for other tumors.

Juxtacortical Chondromyxoid Fibroma of Bone: A Unique Variant

“…In addition to individual case reports, [1][2][3]5,6,8,[11][12][13][14]16,20,[23][24][25]27,30,31,33,34,36,41,[46][47][48]50 there have been multiple reviews of this lesion in which the experience ranging from several to many patients has been summarized. 7,9,10,17,21,29,37,52,55 In its typical presentation, CMF occurs in the intramedullary portion of the metaphysis of long bones in the second to third decade of life.…”

Extragnathic fibromyxoma of the calcaneum: report of a case

“…Occasionally, fibromyxoma originates from flat bones [1–3], but was not previously described in the spongy bones as in our case.…”

Fibromyxoma of the Axis

“…8,14,15,[18][19][20] Fibromyxoma should be distinguished from benign cartilageforming bone tumors, such as chondromyxoid and myxoid chondrosarcoma based on the absences of a histological lobular pattern, chondroid matrix and variety of cells, and the more aggressive behavior of myxoid chondrosarcoma. 1,3,4,8,14,20 Fibromyxoma is also similar to myxoma of bone. 3,9,10 However, myxomas are characterized by the proliferation of primitive mesenchymal cells that produce amorphous intercellular substance.…”

“…The typical location is the jaws. [1][2][3][4] Compared with gnathic tumors, extra gnathic fibromyxoma usually shows benign proliferation and biologic behavior. 3,[5][6][7][8][9][10] Since its original description, 4 sporadic extragnathic cases have been reported.…”

“…3,[5][6][7][8][9][10] Since its original description, 4 sporadic extragnathic cases have been reported. [1][2][3][4][7][8][9][10][11][12][13][14][15][16][17] Predilection sites are the metaphyses of the long bones. Locations in flat and nontubular bones are rare.…”