“…Thus, it is reasonable to expect that a proportion of malaria patients presenting with clouding of consciousness, renal failure, coagulopathy, etc., could have coexisting leptospirosis, particularly in tropical countries like India. The similar clinical presentations of acute malaria, leptospirosis, and other undifferentiated fevers make discrimination on clinical grounds difficult [12]. We report two cases with clinical and laboratory evidence of co-infection with malaria and leptospirosis in India.…”