Feto-maternal osmotic balance at term. A prospective observational study

Abstract

Maternal osmolality was significantly lower than arterial cord osmolality confirming our previous results. The feto-maternal osmotic gradient favors water transport from the mother to the fetus and may increase the fetal risk of water intoxication when the mother ingests or is administered large volumes of electrolyte free solutions.

Disruption of the surfactant protein A receptor SP-R210L(CD245α/MYO18Aα) alters respiratory function and iron sequestration in alveolar macrophages of aged mice

“…One noteworthy KDM4B effector is PPAR, which is central to surfactant metabolism in AMs(33). Relevant triggers of KDM4B expression include hypoxia(32) and osmolarity(34), conditions encountered during gestation and transition from the hypoxia in utero to normoxia in postnatal life(35)(36)(37)(38)(39), and TGF(32) In the present context, AMs may sense changes in oncotic balance in the lung's airway-capillary barrier.…”