Fetal toxicity of Solanum lycocarpum (Solanaceae) in rats

Chang, Claudia Veiga; Felı́cio, André Carvalho; Reis, João Evangelista de Paula; Guerra, Martha de Oliveira; Peters, Vera Maria

doi:10.1016/s0378-8741(02)00092-2

Cited by 40 publications

(28 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Since literature search shows no previous work on the effect of Salacia lehmbachii on pregnancy and fetal development, there are no results on the plant to compare with findings of this work. However, effects of Salacia reticulata, a specie in the genus, Salacia and some other herbs on pregnancy and fetal development have been evaluated [35,[40][41][42][43][44][45][46].…”

Section: Discussionmentioning

confidence: 99%

“…Implantation of the fertilized egg is a critical step of conception and the conception index correlates with the site of implantation and the number of corpora lutea [44]. The implantation index and pre-implantation loss rate evaluate blastocyst implantation in the uterus while the resorption index and post-implantation loss rate establish correlation between the number of implanted blastocysts and those that have not developed [35,41].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Embryotoxic and Teratogenic Potentials of Salacia lehmbachii in Rats

Essiet¹,

Akuodor²,

Essien³

2017

IOSRJPBS

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Embryotoxic and Teratogenic Potentials of Salacia lehmbachii in Rats

Essiet¹,

Akuodor²,

Essien³

2017

IOSRJPBS

View full text Add to dashboard Cite

“…Solanum lycocarpum é uma espécie nativa, empregada na medicina popular para vários fins, principalmente no tratamento do diabetes (Sá et al, 2000;Peters et al, 2001;Chang et al, 2002;Perez, 2006). O infuso de frutos e flores é referido por Rodrigues & Carvalho (2001) contra asmas, gripes, resfriados e também como tônico e as folhas são usadas como emoliente e anti-reumático.…”

Section: Introductionunclassified

“…O "polvilho-de-lobeira" obtido de frutos foi ativo na diminuição dos níveis de colesterol (Dall'agnol & Von Poser, 2000). Estudos confirmaram atividades analgésica, anti-inflamatória (Vieira et al, 2003) e tóxica (Sá et al, 2000;Chang et al, 2002;Mauro et al, 2003). Além disso, foram isolados solamargina e solasodina de frutos (Motidome et al, 1970;Dall'agnol & Von Poser, 2000).…”

Section: Introductionunclassified

Estudo farmacobotânico comparativo de folhas de Solanum crinitum Lam., Solanum gomphodes Dunal e Solanum lycocarpum A. St.-Hil., Solanaceae

Araújo¹,

Coelho²,

Agra³

2010

Rev. bras. farmacogn.

View full text Add to dashboard Cite

RESUMO:Neste trabalho realizou-se um estudo farmacobotânico de Solanum crinitum Lam., Solanum gomphodes Dunal e Solanum lycocarpum A. St-Hil, espécies pertencentes à Solanum sect. Crinitum Child, com o objetivo de efetuar morfodiagnoses macroscópicas e microscópicas que possibilitem suas caracterizações. As três espécies são conhecidas popularmente como "jurubeba", fruta-de-lobo" e "lobeira" e usadas na medicina popular contra o diabetes e também para outros fins. Essas espécies compartilham vários caracteres morfológicos, dentre os quais se destacam o hábito arbustivo a arbóreo, o indumento velutino às vezes cerdoso, a corola é pentagonal-estrelada, roxa a púrpura, e o fruto globoso acima de 5 cm de diâmetro. Entretanto, apesar da grande semelhança morfológica entre as espécies estudadas, destacaram-se como parâmetros distintivos: a morfologia do pecíolo, a base do limbo, o indumento da face adaxial, a anatomia do mesofilo, os tipos de estômatos e a morfologia do bordo foliar.Unitermos: Morfoanatomia, seção Crinitum, Solanaceae, subgênero Leptostemonum.ABSTRACT: "The pharmacobotanical comparative study of leaves of Solanum crinitum Lam., Solanum gomphodes Dunal and Solanum lycocarpum A. St-Hil, (Solanaceae)". In this work, a pharmacobotanical study of Solanum crinitum Lam., S. gomphodes Dunal and S. lycocarpum A. St-Hil., all belonging to the Solanum sect. Crinitum Child. has been realized with the objective of providing a macroscopical and microscopical morphodiagnosis for their characterizations. The three species are commonly named "jurubeba", "fruta-de-lobo" and "lobeira", and they are used in the folk medicine for the treatment of diabetes and other diseases. The three species studied share various morphological characters, like shrub and tree forms, the velutinous abaxial indument, the presence of bristles, the flower with stellate-pentagonal corollas ranging from violet to purple, and the fruit reaching up to 5 cm in diameter. The principal parameters to distinguish the three species studied were the morphology of petiole and base of the blade leaf, the indument of adaxial surface, the anatomy of mesophyll, the types of stomata and the leaf margin.

show abstract

“…It is well established that the implantation index directly correlates to the number of corpora lutea and indicates blastocyst implantation in the endometrium 14 as well as the normal capacity of reproduction. 15 When the data of animal weight was analyzed a fast increase in weight was observed in case of control group animals.…”

Section: Discussionmentioning

confidence: 99%

Anti Fertility and Anti Implantation Effect of Green Tea Aqueous Extract on Female Wistar Rats

Saraswat¹,

K²,

Wal³

et al. 2016

Int. J. Res. Ayurveda Pharm.

View full text Add to dashboard Cite

Green Tea is obtained from the leaves of Camellia Sinensis plant. The green Tea comprises of caffeine as a major constituent. A lot has been listed out on the health benefits of drinking Green Tea. The plant belongs to family Theaceae. The aqueous extract (200mg/kg) was orally given to female wistar rats for fifteen days in treated group and saline solution to control group. We maintained five groups each of control and treated so as to get a clear picture and cumulative result of our research. The male rats were kept in each cage in ratio of 2:1 (Male: Female) from day 2-4 and then withdrawn. When the implantation and fertility studies were carried out a decrease in both the activities (Implantation and Fertility) was reported in case of treated group. The parameters of weight was also studied which reflected a increase in case of control group as compared to treated group. When the results were calculated and observed a decrease in implantation and fertility was shown by treated female rats which were on aqueous green tea dosing. The previous studies have been conducted on male wistar rats which proved a decrease in size of gonads thus helping us to aim at the female wistar rats in our research. The control groups showed a total of 16 implants as compared to the treated groups which collectively showed only 9 implants. This made our observation clear that both the fertility and implantation is affected under regular dosing of Green Tea aqueous extract.

show abstract

Fetal toxicity of Solanum lycocarpum (Solanaceae) in rats

Cited by 40 publications

References 19 publications

Embryotoxic and Teratogenic Potentials of Salacia lehmbachii in Rats

Embryotoxic and Teratogenic Potentials of Salacia lehmbachii in Rats

Estudo farmacobotânico comparativo de folhas de Solanum crinitum Lam., Solanum gomphodes Dunal e Solanum lycocarpum A. St.-Hil., Solanaceae

Anti Fertility and Anti Implantation Effect of Green Tea Aqueous Extract on Female Wistar Rats

Contact Info

Product

Resources

About