2006
DOI: 10.1111/j.1471-0528.2006.00913.x
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Fetal medicine: Intrauterine fetal demise following laser treatment in twin‐to‐twin transfusion syndrome

Abstract: Objective To evaluate the incidence, risk factors and consequences of intrauterine fetal demise (IUFD) of at least one twin in twin-to-twin transfusion syndrome (TTTS) treated by laser.Design Retrospective analysis.Setting Experience of a single centre between 1999 and 2004.Population A subgroup of 45 cases with fetal demise of one or both twins from a series of 120 cases of TTTS treated by laser.Methods All cases were entered prospectively into a dedicated database and the results were analysed retrospectivel… Show more

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Cited by 69 publications
(70 citation statements)
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“…Three of the cases reported here have already been reported. 15 Single IUFD involved 11 donors and 8 recipients. The median gestational age at IUD was 23 [20][21][22][23][24][25][26][27][28] weeks, and the median interval between IUFD and intrauterine transfusion (IUT) was 12 [8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24] hours.…”
Section: Resultsmentioning
confidence: 99%
“…Three of the cases reported here have already been reported. 15 Single IUFD involved 11 donors and 8 recipients. The median gestational age at IUD was 23 [20][21][22][23][24][25][26][27][28] weeks, and the median interval between IUFD and intrauterine transfusion (IUT) was 12 [8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24] hours.…”
Section: Resultsmentioning
confidence: 99%
“…La muerte de un feto ocurre en cerca del 20% luego del procedimiento, pudiendo afectar a donantes o receptores. Diversos estudios han buscado detectar factores de riesgo preoperatorios para predecirla (16,17,18).…”
Section: Discussionunclassified
“…Recent studies report that there is a 10% risk of PPROM with a 10 to 30% risk of fetal death, of at least one of the two twins. 64,76,81,122,132 Another recognized complication of laser treatment is unintentional septostomy of the intertwin membrane. Usually, it can be caused by difficult entry in the uterine cavity close to the donor embryo, where because of the anhydramnios the membrane may not be visible and perforated.…”
Section: Complications Of Laser Treatmentmentioning
confidence: 99%
“…64,89 Fetal MRI after fetal death of one of the twins who were treated with laser for TTTS can detect brain injury much earlier than ultrasound, 64,140,141 and MRI imaging has been suggested by some centers pre and posttreatment for TTTS, and for cases complicated by single twin demise. 64,132,141143 Laser photocoagulation for at least severe cases of TTTS appears to be the best possible option for treatment. However, parents and physicians need to have in mind that TTTS is a very high risk case in terms of perinatal outcomes and that the possibility of death of at least one of the two twins is very high, about 30 to 50% and that even after survival from treatment for TTTS there is a significant risk of long-term neurological impairment ranging from 5 to 20%.…”
Section: Outcome Of Treatment-neonatal Follow-upmentioning
confidence: 99%