Fetal macrosomia in African women: a study of 249 cases

Kamanu, C; Onwere, S; Chigbu, B; Aluka, C; Okoro, O; Obasi, M.

doi:10.1007/s00404-008-0780-7

Cited by 53 publications

(94 citation statements)

References 4 publications

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“…8-22.8). This is in accordance with the findings of Kamanu et al [14] who noticed that past history of delivery of a macrosomic baby was a significant risk factor for the delivery of macrosomic baby in subsequent pregnancies.…”

Section: Discussionsupporting

confidence: 94%

“…Regarding pre-gestational BMI, we observed that women with BMI C25 had slightly increased risk for This is in accordance with the findings of Bergmann et al [13] who noticed that women with pre-gestational BMI C26 kg/m 2 were at increased risk for delivering macrosomic babies, while Kamanu et al [14] found a pre-gestational BMI value of C28 kg/m 2 as cut-off point for the risk for delivering macrosomic babies. Moreover, father's BMI C30 was found in our study to have an influence in the occurrence of macrosomia (OR 3.7, 95 % CI 1.7-6.9).…”

Section: Discussionsupporting

confidence: 93%

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Risk Factors for Macrosomia

Nkwabong

Tangho

2014

J Obstet Gynecol India

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Section: Discussionsupporting

confidence: 94%

Section: Discussionsupporting

confidence: 93%

Risk Factors for Macrosomia

Nkwabong

Tangho

2014

J Obstet Gynecol India

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“…Por otra parte, no pudimos determinar si la cesárea fue electiva o de emergencia. En cualquier caso, debido a que la macrosomía se asoció con la obesidad materna, como se ha reportado previamente (19,20) , la reducción de la obesidad puede reducir la macrosomía, disminuyendo así las complicaciones en el parto y el puerperio y las tasas de cesáreas. Además, la reducción de la macrosomía puede contribuir a prevenir el desarrollo de sobrepeso / obesidad en la infancia (21) .…”

Section: Discussionunclassified

Prevalencia y factores asociados a macrosomía en Perú, 2013

Cunha

Toro

Gutiérrez

et al. 2017

Rev Peru Med Exp Salud Publica

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Objetivos. Determinar la prevalencia de macrosomía y factores asociados en Perú, y describir la ocurrencia de complicaciones durante el parto y posparto. Materiales y métodos. Los pesos al nacer de los niños menores de cinco años fueron analizados usando datos de la Encuesta Demográfica y de Salud Familiar (ENDES) 2013, llevada a cabo por el Instituto Nacional de Estadística e Informática. Los niños con un peso mayor a 4000 g al nacer fueron considerados como macrosómicos. Se empleó un análisis de regresión logística para establecer la asociación independiente de factores sociodemográficos con la macrosomía. Resultados. La muestra estuvo constituida por 6121 niños. La prevalencia de macrosomía fue 5,3% (intervalo de confianza al 95%: 4,8 a 5,9). El sexo masculino, un orden de nacimiento mayor, la obesidad materna y una mayor estatura materna estuvieron independientemente asociados con la macrosomía. Los partos por cesárea fueron más frecuentes en niños macrosómicos (43,9% vs 26,9%). Las complicaciones durante el parto y posparto fueron frecuentes, pero no estadísticamente asociadas con la macrosomía. Conclusiones. La prevalencia de macrosomía en Perú es relativamente baja comparada con otros países de ingresos bajos o medios. Los factores asociados con la macrosomía fueron principalmente no modificables, con excepción de la obesidad materna. Los niños macrosómicos nacieron más frecuentemente por cesárea. La reducción del peso y la prevención de la obesidad en mujeres en edad fértil en Perú podrían potencialmente reducir la macrosomía y las tasas de cesáreas. Palabras clave: macrosomía; factores sociodemográficos, cesárea. (fuente: DeCS BIREME). PREVALENCE AND ASSOCIATED FACTORS OF MACROSOMIA IN PERU, 2013 ABSTRACTObjectives. To determine the prevalence of macrosomia and factors associated with it in Peru and to describe the occurrence of complications peri-and postpartum. Materials and Methods. Birth weights of children under the age of 5 years were analyzed using data from the 2013 Demographic and Family Health Survey (ENDES) carried out by the Instituto Nacional de Estadística e Informática. Children with a birth weight higher than 4000 g were considered macrosomic. A logistic regression analysis was used to establish the independent association of sociodemographic factors with macrosomia. Results. The sample comprised 6121 children. The prevalence of macrosomia was 5.3% (95% interval confidence: 4.8-5.9%). Being male, a higher birth order, maternal obesity, and greater maternal height were independently linked with macrosomia. Caesarean births were more common in macrosomic children than unaffected ones (43.9% vs 26.9%). Complications during birth and postpartum were common but not statistically linked with macrosomia. Conclusions. The prevalence of macrosomia in Peru is relatively low compared to other low-to-middle income countries. The factors associated with macrosomia were mainly unmodifiable, with the exception of maternal obesity. Macrosomic children were more frequently born by caesarean. Weight reduc...

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“…Fetal and neonatal macrosomia induced by maternal diabetes have long been recognized in human pregnancy (Gilmartin et al 2008, Kamanu et al 2009). Macrosomia was also observed in case of increased maternal fat intake (Soulimane-Mokhtari et al 2005, Coe 2006).…”

Section: Discussionmentioning

confidence: 99%

“…Fetal macrosomia often demands the attention of different medical disciplines. It has been previously defined in human as a birth weight above 4000 to 4500 g. It may be associated with a higher risk of birth injury during vaginal delivery (Kamanu et al 2009, Iessi et al 2010, Al-Wazzan and Sarsam 2011. Macrosomia has different causes.…”

mentioning

confidence: 99%

Effect of Diabetes on Skin and Brown Fat of Rat Macrosomic Fetuses: Histological and Histochemical Study

et al. 2015

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SummaryFetal macrosomia is one of the major clinical problems that carry health hazards for both mother and fetus. Diabetic mothers with mild hyperglycemia or gestational diabetes are at a high risk of having macrosomic babies. This study aimed to describe the cellular changes of skin and brown fat of macroscomic fetuses born to mildly diabetic rats. This experimental study used 36 adult female rats divided into control (n=12) and experimental (n=24) groups. The latter were injected intra-peritoneally with Alloxan (100 mg/kg) and animals with blood glucose (130-250) mg/mL (n=16) were designated as diabetic and were housed with known fertile males. On day 21 of gestation, pregnant females were sacrificed and fetuses were weighted and processed for histological and histochemical examination. A significant increase in body weight of macrosomic fetuses born to diabetic mothers (6.6 0.37) was recorded. Mean dermal thickness (7.9 0.2) and brown fat mass (451.8 11.2) were significantly increased (p=0.004 and p=0.04) in macrosomic fetuses. Brown fat adipocytes showed earlier transformation into white fat adiopocytes. Lipid and polysaccharide accumulation as well as significant cell proliferation were observed in both tissues of macrosomic fetuses. Increased thickness of skin and mass of fat brown fat of macrosomic fetuses of mild diabetic rats could be attributed to increased deposition of polysaccharides and lipids as well proliferation of their cells.

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Fetal macrosomia in African women: a study of 249 cases

Abstract: The higher the total body weight at birth, the higher the rate of macrosomia. Macrosomia had implications for high morbidity and mortality in the mothers and their infants. Delivery methods need to be evaluated. Caesarean section should be more readily used.

Cited by 53 publications

References 4 publications

Risk Factors for Macrosomia

Risk Factors for Macrosomia

Prevalencia y factores asociados a macrosomía en Perú, 2013

Effect of Diabetes on Skin and Brown Fat of Rat Macrosomic Fetuses: Histological and Histochemical Study

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