Fetal karyotypes from fetoscopy blood samples

Abstract

The fetal karyotype was determined in 42 out of 45 cases from fetal blood obtained by fetoscopy for prenatal diagnosis of beta-thalassemia. The procedure described is quick and reliable and it is recommended for women over 35 years of age undergoing prenatal diagnosis for haemoglobinopathies.

Fetoscopy in prenatal diagnosis of the Majewski and the Saldino‐Noonan types of the Short Rib‐Polydactyly syndromes

“…Fetoscopy is used for two different purposes, namely visualization and sampling. The largest number of fetoscopies has been performed for the purpose of sampling cord blood for haemoglobin analysis in diagnosis of haemophilia and haemoglobinopathies (Bloom & Peake 1981, Model1 & Ward 1981, but during the past few years reports on blood sampling for lymphocyte culture for various purposes (Durandy et al 1982, Metaxotou et al 1983, Webb et al 1983), skin sampling for diagnosis of inborn errors of metabolism (Blanchet-Bardon et al 1983), and recently also fetoscopic liver biopsy (Rodeck et al 1982) have emerged.…”