Fetal Disease and Abortion

Baumgartner, Wes

doi:10.1002/9781119602484.ch56

Cited by 3 publications

(1 citation statement)

References 180 publications

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“…A significant increase in stillbirths was observed when mating AH1 bulls with daughters of AH1 bulls [14,22,25]. This is alarming, since all available records were taken into account when registering stillbirths, without a detailed analysis of the causes of each, although factors such as trauma and/or infectious disease in the mother, malnutrition, and energy imbalance can also be causes of stillbirth [1]. In our work, we show, for the first time, that the risk of having a dead calf is increased in heifers and cows that are daughters of AH1-C bulls.…”

Section: Analysis Of Calving Results and Reproductive Qualities Of Co...mentioning

confidence: 99%

VARIANT RS475678587C>T OF THE UBE3B GENE (HAPLOTYPE AH1) IN AYRSHIRE CATTLE INCREASES THE RISK OF STILLBIRTH IN DAUGHTERS OF MALE CARRIERS

Tulinova

Vasilyeva

Romanova

et al. 2022

SJLSA

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The aim of our study was to analyze the reproduction dynamics and fertility rates of the Ayrshire cattle population in Russia and to assess the level of influence of the AH1 haplotype on the incidence of stillbirth. For an overall fertility estimate, we used 390,769 records of 67 dairy herds in Russia from 2003 to 2018. Against the background of stable population growth, the average stillbirth rate was 3.33% and the abortion rate was 0.075%. A high percentage of stillbirth (5.13%) from heifers the first fertilization event, and there was a high rate of abortions in older cows (11 calving, 1.76%). An analysis of 62,534 records of bulls with the rs475678587C>T variant of UBE3B gene (AH1 haplotype) (n = 69, of which 51 bulls were free from and 18 were carriers of AH1) for the period 2002 to 2018 showed that the proportion of female offspring of AH1-C bulls completing at least one full period of lactation was about one-third of the total livestock. An analysis of the results of mating with AH-F and AH-C bulls for the broodstock as a whole (without taking into account the female genotype) did not reveal significant differences in the number of stillbirths and abortions. Linear regression analysis showed that the status of AH1 bulls did not significantly affect stillbirth rates. An analysis of the results of calving and the reproductive ability of the offspring of AH-C bulls showed an increase in the frequency of stillbirths, confirmed by the results of linear regression analysis, which revealed a significant effect of bull fathers carrying AH1on the proportion of stillbirths experienced by their daughters. Our studies confirm that the rs475678587C>T variant of the UBE3B gene (haplotype AH1) has a significant effect on the rate of stillbirth of a cow or heifer if their father is a carrier of this genetic defect.

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Section: Analysis Of Calving Results and Reproductive Qualities Of Co...mentioning

confidence: 99%

VARIANT RS475678587C>T OF THE UBE3B GENE (HAPLOTYPE AH1) IN AYRSHIRE CATTLE INCREASES THE RISK OF STILLBIRTH IN DAUGHTERS OF MALE CARRIERS

Tulinova

Vasilyeva

Romanova

et al. 2022

SJLSA

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Hydrops amnion in a Belgian blue cow combined with prolonged gestation and anencephaly of the calf

Kemel

Brack

Schroyen

et al. 2022

Vet Record Case Reports

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In cattle, hydrops amnion is a rare pathological condition. In the present study, we report such a case in a Belgian blue cow suffering from prolonged gestation. A presumptive diagnosis was based on clinical examination, including transrectal ultrasonography. Management included inducing parturition with dinoprost and dexamethasone, where 36 hours later, a left flank recumbent caesarean section was performed. A live, oversized, male calf (76 kg) with a frontal cephalocele/meningocele was delivered. Postmortem examination revealed anencephaly, characterised by the absence of the cerebrum. Intravenous fluid therapy was administered during surgery to prevent hypovolemic shock, and postoperative treatment consisted of intramuscular injections of 100 IU of oxytocin and antibiotics (procaine benzylpenicillin) for 3 consecutive days. After 5 days, the patient was discharged from the clinic.

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Bovine infectious abortion: a systematic review and meta-analysis

Hecker,

González-Ortega,

Cano

et al. 2023

Front. Vet. Sci.

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The aim of the present systematic review and meta-analysis was to identify the main infectious agents related to bovine abortion worldwide in the period between 2000 and 2022. First, we investigated the global prevalence of infectious agents related to bovine abortion. For this analysis, only 27 articles detected of a wide panel of agents were included. The random effects model revealed that the estimated prevalence of the abortifacient agents in bovine abortion was 45.7%. The heterogeneity among studies was high, but Egger’s test showed that there was no publication bias, even though the total number of samples analyzed in these articles was variable. There was no significant effect of the year of the study publication on the estimated prevalence, although an increasing trend was observed over time, possibly due to the implementation of new diagnostic techniques. Then, we analyzed the prevalence of the main transmissible agents in bovine abortion. For this analysis, 76 studies that analyzed 19,070 cases were included. Some infectious agent was detected in 7,319 specimens, and a final diagnosis was reached in 3,977 of these, when both the infectious agent and compatible histopathological changes were detected. We found that Neospora caninum was the most detected agent (22.2%), followed by opportunistic bacteria (21.4%), Chlamydiaceae family (10.9%) and Coxiella burnetii (9.5%). Regarding viral agents, bovine herpes virus type 1 and bovine viral diarrhea displayed similar prevalence rates (approximately 5%). After considering the description of specific histopathological changes, our analyzes showed that N. caninum was a confirmed cause of abortion in 16.7% of the analyzed cases, followed by opportunistic bacteria (12.6%) and Chlamydia spp. (6.8%); however, C. burnetii was only confirmed as a cause of abortion in 1.1% of the cases. For all agents, the heterogeneity among studies was high, and the subgroup analyzes discarded the diagnostic method as the cause of such heterogeneity. This study provides knowledge about the global prevalence of the different infectious agents related to bovine abortion, the most coming of which is N. caninum. In addition, this review reveals the existing deficiencies in the diagnosis of bovine abortion that must be addressed in the future.

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Fetal Disease and Abortion

Cited by 3 publications

References 180 publications

VARIANT RS475678587C>T OF THE UBE3B GENE (HAPLOTYPE AH1) IN AYRSHIRE CATTLE INCREASES THE RISK OF STILLBIRTH IN DAUGHTERS OF MALE CARRIERS

VARIANT RS475678587C>T OF THE UBE3B GENE (HAPLOTYPE AH1) IN AYRSHIRE CATTLE INCREASES THE RISK OF STILLBIRTH IN DAUGHTERS OF MALE CARRIERS

Hydrops amnion in a Belgian blue cow combined with prolonged gestation and anencephaly of the calf

Bovine infectious abortion: a systematic review and meta-analysis

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