Fetal cardiac rhabdomyoma with maternal tuberous sclerosis complicating pregnancy

Abstract

To conclude, a pregnancy complicated by maternal or fetal tuberous sclerosis deserves careful vigilance and the fetus should undergo prenatal fetal Doppler echocardiography and if possible an MRI, so that parents can be counseled regarding its future prognostic implications.

Fetal cardiac tumor: echocardiography, clinical outcome and genetic analysis in 53 cases

“…Cardiac rhabdomyoma, however, may be the initial manifestation of tuberous sclerosis complex (TSC). TSC is an autosomal dominant genetic disease involving multiple systems, including the skin, central nervous system, heart, eyes, kidneys and lungs.…”

Diverse presentation of connective tissue disorders in pregnancy

“…In infants, cardiac involvement and seizures are common presenting signs whereas skin and other organ involvement may suggest diagnosis in older individuals. 8 In mother, neurological complications like intractable epilepsy, status epilepticus and subependymal giant cell astrocytoma (SEGA) are the most common cause of mortality and morbidity. Renal complications are the next most frequent cause.…”

Fetal Bradyarrythmia: Are We Missing Something?

“…Arrhythmias include supraventricular tachycardia, ventricular tachy, or bradyarrhythmia. Intrauterine cardiac arrhythmias have been frequently detected during routine fetal heart monitoring and an association with structural congenital heart which has been reported [4]. Arrhythmias resolve with regression of rhabdomyomas.…”