Fertility-Sparing Hysterotomy in Malignant Trophoblastic Tumours Treatment

Abstract

The aim is to improve treatment efficacy and life quality of patients with malignant trophoblastic tumours. Fertility-sparing hysterotomy with uterine reconstruction was carried in 16 patients aged of 17 to 32 years: 2 cases due to urgent and 13 – due to planned indications. On the basis of research, the indications for the urgent and planned fertility-sparing hysterotomy with uterine reconstruction in patients with malignant trophoblastic tumours were formulated. No postoperative complications. Steady remission in all cases. Follow up from 1 to 17 years (averaged 9.2 years). 1. Localized uterine resection with uterine reconstruction – the method of choice in malignant trophoblastic tumours surgical treatment; 2. Fertility-sparing hysterotomy with uterine reconstruction is only possible in centers which are experienced in the complex multimodality treatment of gestational trophoblastic neoplasms; 3. Basic requirement of fertility-sparing surgery is beginning adjuvant chemotherapy as soon as possible.

Non-linear dynamics theory and malignant melanoma

“…A broad perspective was adopted by Ukrainian researchers in their investigations devoted to the application of chaos theory to oncology [22][23][24][25][26][27][28].…”