Fertility- and Menopause-Related Information Needs of Younger Women With a Diagnosis of Early Breast Cancer

Thewes, Belinda; Meiser, Bettina; Taylor, Alan; Phillips, Kelly‐Anne; Pendlebury, Susan; Capp, Anne; Dalley, D.; Goldstein, David; Baber, Rod; Friedlander, Michael

doi:10.1200/jco.2005.07.773

Cited by 228 publications

(245 citation statements)

References 36 publications

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“…The success rates of these options range from 5 to 25% . Despite an increasing number of studies and guidelines demonstrating the need for discussion of FP issues with cancer patients, information provision about treatment-induced infertility and FP techniques and referral for FP are still not sufficient and often provided too late (Dunn & Steginga, 2000;Jenninga, Hilders, Louwe, & Peters, 2008;Nakayama et al, 2009;Quinn et al, 2007;Rosen, Rodriguez-Wallberg, & Rosenzweig, 2009;Thewes et al, 2005;Tschudin & Bitzer, 2009). …”

Section: Introductionmentioning

confidence: 99%

Feasibility and effects of a decision aid about fertility preservation

et al. 2016

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This paper reports on the feasibility and preliminary effects of a decision aid (DA) about female fertility preservation (FP). We conducted a pilot multicentre randomized controlled trial of women with breast cancer aged 18-40 who were randomized to brochures or the DA. Over 18 months, 62 women were eligible, of which 42 were invited by their healthcare provider (74%) to participate in the study. A total of 36 women signed up for participation and 26 (72%) were randomized to brochures (n ¼ 13) or the DA (n ¼ 13). In both groups, many women (87%) read the brochures and eight women used all available brochures. In the intervention group, 7/13 women logged in to the DA. Women who received brochures had slightly less decisional conflict, whereas knowledge improved in both groups. Our results indicate that both brochures about FP and a detailed DA have beneficial effects with regard to knowledge, but the DA seemed to introduce slightly more decisional conflict (DC) than the brochures. Although we encountered challenges with recruitment, our design and measurements seem feasible and the effects of the information materials seem promising, hence justifying conducting a larger study. ARTICLE HISTORY

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Section: Introductionmentioning

confidence: 99%

Feasibility and effects of a decision aid about fertility preservation

et al. 2016

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“…Although breast cancer is typically a disease of elderly women, approximately 6% of cases occur in women less than 40 years of age, and the 5-year survival rate for those women is approximately 85% [1][2][3] . Consequently, the longterm toxicities of breast cancer treatment are of increasing relevance, and several studies have found that fertilityrelated concerns greatly affect quality of life for young breast cancer survivors [3][4][5][6] .…”

Section: Introductionmentioning

confidence: 99%

Ovarian Function after Chemotherapy in Young Breast Cancer Survivors

et al. 2017

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“…The increase in disease-free survival (DFS) and the decrease in overall mortality are most likely a result of increased awareness of breast diseases, well-established screening programs leading to earlier detection, and better treatment, which includes more liberal use of adjuvant cytotoxic chemotherapy and hormonal therapy [6][7][8][9]. Coupled with the increase in the number of women who delay first childbirth beyond the age of 35, the use of adjuvant chemotherapy regimens has resulted in a large proportion of breast cancer patients of reproductive age facing infertility [10][11][12].…”

Section: Introductionmentioning

confidence: 99%