Fertility and contraceptive issues after kidney transplantation in women

Lessan‐Pezeshki, Mahboob; Ghazizadeh, Shirin; Khatami, Mohammad Reza; Mahdavi, Mahdi; Razeghi, Effat; Seifi, Sepideh; Ahmadi, Farokhlagha; Maziar, Sima

doi:10.1016/j.transproceed.2004.04.090

Cited by 65 publications

(38 citation statements)

References 4 publications

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“…Additionally, the false assumption about the high infertility rate in renal transplant recipients may greatly influence this result. Previous data and our study findings indicate that the infertility rate was nearly 10% among transplant recipients, which is not different from the normal population [35,36]. Stressing the need for psychological stability as a major requirement for being an allograft recipient is important - 1 of the patients with schizophrenia had a rejection due to the discontinuation of immunosuppressive therapy.…”

Section: Discussionmentioning

confidence: 49%

A Retrospective Analysis of Pregnancy Outcomes after Kidney Transplantation in a Single Center

Akar

Ozekinci

Sanhal

et al. 2014

Gynecol Obstet Invest

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Background: We reported pregnancy outcomes after kidney transplantation in a single transplant center. Methods: We reviewed the perinatal outcomes of female kidney transplant patients of reproductive age (18-40 years) from 1987 to 2011. Results: A total of 246 patients were reviewed. Of these, 43 women registered a pregnancy following kidney transplantation. The mean patient age was 31.3 ± 4.2 years (range 24-40). The mean transplant-conception interval was 35.9 ± 12.6 months (range 24-120); 9 patients had a cadaveric allograft. The human leukocyte antigen match was ≥3/6 for 34 patients. The rate of live births was 29/43 (67.4%), miscarriage 10/43 (23.2%), preterm delivery 7/29 (24.1%), preeclampsia 5/29 (17.2%), and intrauterine growth retardation 2/29 (6.9%). Overall, 3/29 patients (10.3%) received a blood transfusion during pregnancy due to persistent symptomatic anemia, despite iron replacement and erythropoietin therapy; 24 patients (82%) had a cesarean section delivery; 3 patients had kidney rejection during pregnancy, with 2 occurring during the 6th postpartum month. Conclusion: Pregnancy should be considered a high risk in renal transplant recipients, necessitating close follow-up.

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Section: Discussionmentioning

confidence: 49%

A Retrospective Analysis of Pregnancy Outcomes after Kidney Transplantation in a Single Center

Akar

Ozekinci

Sanhal

et al. 2014

Gynecol Obstet Invest

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“…Intrauterine devices are not optimal because they require an intact immune system for efficacy (31). Progestin-only oral contraceptives as well as estrogen/progestin are probably acceptable for use in this patient population as long as hypertension is well controlled (32)(33)(34). The best contraceptive agent to use after transplantation depends on considerations, made between the patient and her physician, of the desirability of pregnancy and considerations of the risks and benefits of each contraceptive method (30).…”

Section: Fertility Contraception and Optimal Timing Of Pregnancymentioning

confidence: 99%

Pregnancy after Kidney Transplantation

McKay

Josephson²

2008

Clinical Journal of the American Society of Nephrology

127

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Reproductive success is a common, expected outcome for male and female recipients of solid-organ transplants. Men can father children, and women can become pregnant and carry the fetus to delivery. There are, however, important maternal and fetal complications that need to be considered to provide optimal care to the mother and her infant. Although pregnancy is common after the transplantation of all solid organs, guidelines for optimal counseling and clinical management are limited. This review discusses information to help the physician counsel the kidney transplant recipient about risks of pregnancy for the mother and the fetus and provides information to help guide treatment of the pregnant transplant recipient.

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“…[4] Yapılan çalış-malarda canlı doğum oranlarında transplantasyon ile artış saptanırken preeklampsi, gestasyonel diyabet, sezaryen ve preterm doğumlarda genel popülasyo-na göre daha yüksek oranlar tespit edilmektir. [2] Fetal büyüme geriliği renal transplantlı hastalarda %20 -30 oranında görülmekteyken, erken doğum %45-60 oranında bildirilmiştir.…”

Section: Discussionunclassified