Ferric-o-phenanthroline adsorbed on a Nafion membrane: A novel optical sensor for antioxidant capacity measurement of food extracts

Bener, Mustafa; Apak, Reşat

doi:10.1016/j.snb.2017.03.017

Cited by 18 publications

(18 citation statements)

References 42 publications

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“…Thus, the novel method could be a substitute for the modified antioxidant capacity assays [ 44 ]. A sensitive solid membrane optical sensor was proposed for evaluating the antioxidant capacity of fruit juices [ 10 ]. The functionality of the sensor was dependent on immobilizing a chromogenic oxidant, Fe(III)-o-phenanthroline (Fe(III)-phen), onto a Nafion cation-exchange membrane.…”

Section: Optical Sensors and Assaysmentioning

confidence: 99%

“…The sensor was more sensitive than the solution-phase method because the membrane concentrated the color from a larger volume solution. Also, this sensor was easily adaptable to a kit format [ 10 ].…”

Section: Optical Sensors and Assaysmentioning

confidence: 99%

“…Antioxidants combat diseases that are derived from oxidative stress such as heart disease, cancer, diabetes, cardiovascular diseases, neurodegenerative disorders, AIDS, ageing, arthritis, asthma, autoimmune diseases, Alzheimer’s disease, Parkinson’s dementia, hypertension, cataracts, etc. [ 7 , 8 , 9 , 10 , 11 ]. Oxidative stress is a devastating procedure caused by high levels of reactive oxygen/nitrogen species (ROS/RNS) or depletion of the antioxidant matrix.…”

Section: Introductionmentioning

confidence: 99%

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An Overview of Optical and Electrochemical Sensors and Biosensors for Analysis of Antioxidants in Food during the Last 5 Years

Nejadmansouri

Majdinasab

Nunes

et al. 2021

Sensors

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Antioxidants are a group of healthy substances which are useful to human health because of their antihistaminic, anticancer, anti-inflammatory activity and inhibitory effect on the formation and the actions of reactive oxygen species. Generally, they are phenolic complexes present in plant-derived foods. Due to the valuable nutritional role of these mixtures, analysis and determining their amount in food is of particular importance. In recent years, many attempts have been made to supply uncomplicated, rapid, economical and user-friendly analytical approaches for the on-site detection and antioxidant capacity (AOC) determination of food antioxidants. In this regards, sensors and biosensors are regarded as favorable tools for antioxidant analysis because of their special features like high sensitivity, rapid detection time, ease of use, and ease of miniaturization. In this review, current five-year progresses in different types of optical and electrochemical sensors/biosensors for the analysis of antioxidants in foods are discussed and evaluated well. Moreover, advantages, limitations, and the potential for practical applications of each type of sensors/biosensors have been discussed. This review aims to prove how sensors/biosensors represent reliable alternatives to conventional methods for antioxidant analysis.

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Section: Optical Sensors and Assaysmentioning

confidence: 99%

Section: Optical Sensors and Assaysmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

An Overview of Optical and Electrochemical Sensors and Biosensors for Analysis of Antioxidants in Food during the Last 5 Years

Nejadmansouri

Majdinasab

Nunes

et al. 2021

Sensors

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“…The phenanthroline colorimetry method was adopted [14] for use in this study. The reaction system consisted of 2.0 mL of PBS solution (pH 7.4, 0.01 M), 1.0 mL of phenanthroline reagent (7.50 M), 1.0 mL of ferrous sulfate solution (7.50 M), 3.0 mL of WST extract (0.0, 0.2, 0.6, 1.0 mg/mL), and 2.0 mL of hydrogen peroxide solution (0.06%), which were added in the above order.…”

Section: Oh Free-radical Scavenging Activitymentioning

confidence: 99%

Evaluation of in Vitro Bio-Activities Effects of WST (Wushanshencha)

Liu

Zhang³

et al. 2019

Applied Sciences

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As a traditional Chinese drink, tea is favored for its rich flavor and its medicinal functionality. In this study, the in vitro bioactivities of Wushanshencha (WST; a local tea from Chongqing, China), which is processed mainly from the leaves of the wild Malus hupehensis (Pamp.) Rehd.). We assessed the scavenging capacity of tea extracts on 1, 1-diphenyl-2-picrylhydrazyl (DPPH); 2, 2′-azino-bis (3-ethylbenzthiazoline-6- sulphonic acid) diammonium salt (ABTS); and hydroxyl (OH) free radicals, and demonstrate the high antioxidant activity and dose-dependent relationship of these extracts. We also detail the anti-mutagenic effect of these tea extracts against the Salmonella typhimurium TA98 strain induced by the 2, 7-diaminofluorene (2, 7-AF) mutagen and the TA100 strain induced by the N-methyl-N′-nitro- N- nitrosoguanidine (MNNG) mutagen at concentrations of 1.25 and 2.50 mg/plate, respectively, with the high-dose groups showing better results. We investigated the anticancer mechanisms of WST extracts (40, 100, and 160 μg/mL) in HepG2 human hepatoma cells via 3-(4, 5-dimethyl-2-thiazolyl)-2, 5-diphenyl-2-H-tetrazolium bromide (MTT) assay and quantitative real-time reverse transcription-polymerase chain reaction (RT-qPCR). The results showed that the proliferation of HepG2 cells was significantly inhibited in a dose-dependent manner by the tea extracts. Moreover, apoptosis in HepG2 cells was induced via upregulation of Caspase-3, Caspase-7, Caspase-8, Caspase-9, p21, p53, and Bax as well as downregulation of Bcl-2 apoptosis-associated factors, as assessed via mRNA expression levels after treating with WST extracts. The expression of inflammation-related factors, e.g., NF-κB, and Cox-2, was significantly downregulated by the WST extracts, demonstrating its inflammatory properties. Together, these observations indicated that WST extracts have anti-inflammatory and anti-cancer properties. In addition, high-performance liquid chromatography (HPLC) analysis showed that WST extracts contained chlorogenic acid, 4-hydroxycinnamic acid, isoquercitrin, taxifolin, quercitrin, rosmarinic acid, myricetin, baicalin, neosperidin dihydrochalcone, and quercetin. As such, WST appears to be an effectively functional drink, due to its rich functional components and anti-cancer activity.

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“…Another Nafion membrane-based TAC sensor recently developed in our laboratory utilized the Fe(III)- o -phenanthroline (Fe(III)-phen) reagent immobilized on Nafion, to which antioxidants donated an electron to convert it to the highly colored Fe(II)-phen complex, remaining on the membrane after electron-transfer [ 7 ]. The absorbance of the orange-red colored complex retained by Nafion was measured at 510 nm, yielding a high sensitivity for antioxidants (e.g., the LOD for trolox was 0.26 μmol·L −1 ) and good linearity over a wide concentration range.…”

Section: Design Strategies and Accomplishments For Colorimetric Sementioning

confidence: 99%

Novel Spectroscopic and Electrochemical Sensors and Nanoprobes for the Characterization of Food and Biological Antioxidants

Apak

Çekiç

Üzer

et al. 2018

Sensors

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Since an unbalanced excess of reactive oxygen/nitrogen species (ROS/RNS) causes various diseases, determination of antioxidants that can counter oxidative stress is important in food and biological analyses. Optical/electrochemical nanosensors have attracted attention in antioxidant activity (AOA) assessment because of their increased sensitivity and selectivity. Optical sensors offer advantages such as low cost, flexibility, remote control, speed, miniaturization and on-site/in situ analysis. Electrochemical sensors using noble metal nanoparticles on modified electrodes better catalyze bioelectrochemical reactions. We summarize the design principles of colorimetric sensors and nanoprobes for food antioxidants (including electron-transfer based and ROS/RNS scavenging assays) and important milestones contributed by our laboratory. We present novel sensors and nanoprobes together with their mechanisms and analytical performances. Our colorimetric sensors for AOA measurement made use of cupric-neocuproine and ferric-phenanthroline complexes immobilized on a Nafion membrane. We recently designed an optical oxidant/antioxidant sensor using N,N-dimethyl-p-phenylene diamine (DMPD) as probe, from which ROS produced colored DMPD-quinone cationic radicals electrostatically retained on a Nafion membrane. The attenuation of initial color by antioxidants enabled indirect AOA estimation. The surface plasmon resonance absorption of silver nanoparticles as a result of enlargement of citrate-reduced seed particles by antioxidant addition enabled a linear response of AOA. We determined biothiols with Ellman reagent−derivatized gold nanoparticles.

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Ferric-o-phenanthroline adsorbed on a Nafion membrane: A novel optical sensor for antioxidant capacity measurement of food extracts

Cited by 18 publications

References 42 publications

An Overview of Optical and Electrochemical Sensors and Biosensors for Analysis of Antioxidants in Food during the Last 5 Years

An Overview of Optical and Electrochemical Sensors and Biosensors for Analysis of Antioxidants in Food during the Last 5 Years

Evaluation of in Vitro Bio-Activities Effects of WST (Wushanshencha)

Novel Spectroscopic and Electrochemical Sensors and Nanoprobes for the Characterization of Food and Biological Antioxidants

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