Fermented black rice and blueberry with Lactobacillus plantarum MG4221 improve UVB-induced skin injury

Abstract

Chronic ultraviolet (UV) exposure causes skin injury thorough the production of reactive oxygen species (ROS). Skin dryness, a characteristic of UV-induced injury, is closely related to skin barrier dysfunction. We investigated the effect of fermented black rice and blueberry with Lactobacillus plantarum (FBBBR) on UVB-induced skin injury. In vitro, FBBBR suppressed UVB-induced ROS generation, apoptosis, and metalloproteinase-9 expression, while increasing the expression of collagen type 1 alpha 1 (COL1A1) gene and natural moisturising factor-related genes such as filaggrin (FLG) and transglutaminase-1 (TGM-1). Oral administration of FBBBR increased serum catalase activity and decreased serum IgE levels, improved stratum corneum hydration and epidermal thickness and enhanced FLG, TGM-1, involucrin, and COL1A1 mRNA expression in dorsal skin in UVB-irradiated hairless mice. Therefore, we suggest that FBBBR can be used as a functional food with beneficial effects on skin hydration and skin barrier function.

Andrographis paniculata Leaves Extract Alleviates UVB-Induced HaCaT Cells Through Suppressing Mitogen-Activated Protein Kinases Activation

“…Notably, ALE treatment exhibited significant enhancement PPAR-α expression in UVB-induced HaCaT cells, subsequently stimulating the synthesis of critical genes responsible for forming the skin's protective barrier, including filaggrin and loricrin. 12,21,23 This augmentation firmly emphasizes ALE's potentialities in nurturing skin health and preserving equilibrium by increasing the PPAR-α, HAS-1, AQP3, and loricrin expression in UVB-challenged HaCaT cells. 24,25 Delving deeper, the study delved into ALE's impact on genes integral to bolstering the skin's barrier function.…”

Potential Role of Dietary Salmon Nasal Cartilage Proteoglycan on UVB-Induced Photoaged Skin

“…After overnight incubation, the membranes were washed thrice with TBST and incubated with a secondary antibody (rabbit anti-goat IgG-HRP; mouse anti-rabbit IgG-HRP, Santa Cruz Biotechnology, Dallas, TX, USA). Protein bands were visualized using Pierce ECL western blotting substrate (Thermo Fisher Scientific) and quantified using a ChemiDoc (Bio-Rad) ( Park et al ., 2021 ; Ahn et al ., 2022 ; Liang et al ., 2022 ).…”

Gochujang, a traditional Korean fermented food, protects through suppressed inflammatory pathways and histological structure disruption in dextran sodium sulfate (DSS)-induced colitis mice

“…Recently, there has been considerable interest in improvements through fermentation and bioconversion [ 30 ]. Fermented or bioconversion materials have been reported for their heightened impact on ingredients and beneficial bacteria (prebiotics and probiotics) showcasing effectiveness in antioxidant, anti-inflammatory, skin moisturizing, elasticity, atopic dermatitis, and influencing cardiovascular health [ [30] , [31] , [32] ].…”